TULANE COBRE: TRANSGENIC & GENE-TARGETED ANIMAL CORE

TULANE COBRE：转基因

• 批准号: 7725306
• 负责人: Kailash N Pandey
• 金额: $ 14.06万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7725306
• 关键词: Animals; Arts; Blood Pressure; Cardiovascular Diseases; Cardiovascular system; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Faculty; Functional disorder; Funding; Gene Targeting; Genetically Engineered Mouse; Grant; Homeostasis; Hypertension; Institution; Maintenance; Mentors; Methods; Molecular; Mus; Postdoctoral Fellow; Rat Strains; Research; Research Personnel; Resources; Source; Transgenic Organisms; United States National Institutes of Health; blood pressure regulation; mouse model; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The transgenic and gene-targeted Animal Core Facility serves as a valuable resource for the maintenance and study of genetically engineered mouse and rat strains that will contribute to the understanding of the pathophysiology of hypertension and the molecular mechanisms regulating blood pressure and cardiovascular disease states. This facility will provide investigators access to unique resources and standardized methods to characterize transgenic and gene-targeted mice. Overall, the animal core provides access to unique state-of-the-art standardized methods to further characterize the novel transgenic and gene-targeted mouse models to study the blood pressure regulation and cardiovascular homeostasis. The core helps support projects from junior faculty investigators as well as several of the senior mentors and postdoctoral fellows.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 转基因和基因靶向的动物核心设施是维持和研究基因工程小鼠和大鼠菌株的宝贵资源，这些资源将有助于对高血压的病理生理学以及调节血压和心血管疾病状态的分子机制的理解。该设施将为调查人员提供独特的资源和标准化方法，以表征转基因和靶向基因的小鼠。总体而言，动物核心提供了获得独特的最先进的标准化方法，以进一步表征新型的转基因和基因靶向小鼠模型，以研究血压调节和心血管稳态。核心帮助支持初级教师调查员以及几位高级导师和博士后研究员的项目。