USER TRAINING AND SUPPORT FOR BIO-SAXS/D DATA ACQUISITION AND DATA ANALYSIS SOFT

BIO-SAXS/D 数据采集和数据分析软件的用户培训和支持

• 批准号: 7721866
• 负责人: MARC NIEBUHR
• 金额: $ 3.83万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7721866
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Computer software; Data; Data Analyses; Data Collection; Data Quality; Development; Equipment; European; Funding; Grant; Hand; Institution; Radiation; Research; Research Personnel; Resources; Sampling; Schools; Solutions; Source; Training; Training Support; United States National Institutes of Health; computerized data processing; data acquisition; experience; improved; instrument; posters; programs; radius bone structure; research study; synchrotron radiation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The SSRL BTP staff provides hands-on user training for the effective use of the SMB SAXS/D instrument. Users receive a short tutorial on Blu-ICE used for the majority of non-crystalline scattering and diffraction experiments. They also receive training on the use of MarParse, the data processing program for solution scattering developed recently by the BTP staff, as well as its GUI version MarParseDlg. Users are instructed on the basics in solution x-ray scattering data analysis, such as inspecting data for possible radiation-induced aggregation, subtracting the background, and calculating radii of gyration. The data processing program Fit2D, developed at the European Synchrotron Radiation Facility, as well as Primus from EMBL-Hamburg are also covered upon request. We cover introductory tutorials to the sophisticated solution scattering data interpretation software packages, developed by Dr. Svergun (EMBL-Hamburg). We advise users on practical experimental aspects on experiment geometries, sample-handling equipment, and data collection strategies especially for minimizing radiation damage to help improve data quality. These are given to new user groups and have been found useful also for experienced users. We co-hosted the SMB summer school in September and included extensive versions of the tutorials mentioned above. We presented a poster on our instrumental developments at the SSRL/LCLS users meeting this year to provide our users up-to-date information on our developments.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 SSRL BTP 工作人员提供实际用户培训，以帮助有效使用 SMB SAXS/D 仪器。 用户会收到有关用于大多数非晶体散射和衍射实验的 Blu-ICE 的简短教程。他们还接受了关于使用 MarParse 的培训，MarParse 是 BTP 工作人员最近开发的解决方案分散数据处理程序及其 GUI 版本 MarParseDlg。指导用户了解溶液 X 射线散射数据分析的基础知识，例如检查数据是否存在可能的辐射引起的聚集、减去背景以及计算回转半径。 根据要求，还可涵盖欧洲同步辐射设施开发的数据处理程序 Fit2D 以及 EMBL-Hamburg 的 Primus。 我们介绍了由 Svergun 博士（EMBL-汉堡）开发的复杂解决方案散射数据解释软件包的介绍性教程。我们为用户提供关于实验几何、样品处理设备和数据收集策略等实际实验方面的建议，特别是最大限度地减少辐射损伤，以帮助提高数据质量。 这些是提供给新用户组的，并且被发现对有经验的用户也很有用。我们于 9 月份共同主办了 SMB 暑期学校，其中包括上述教程的广泛版本。我们在今年的 SSRL/LCLS 用户会议上展示了我们仪器开发的海报，为用户提供有关我们开发的最新信息。