TARGETING OF PROTEINS TO THE PROTEASOME DURING SPERMATOGENESIS

精子发生过程中蛋白质靶向蛋白酶体

• 批准号: 7722284
• 负责人: HERMANN STELLER
• 金额: $ 0.11万
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7722284
• 关键词: Cell Death; Computer Retrieval of Information on Scientific Projects Database; Funding; Genetic; Grant; Institution; Proteins; Proteomics; Research; Research Personnel; Resources; Source; Spermatogenesis; Techniques; Testis; United States National Institutes of Health; multicatalytic endopeptidase complex; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Using a combination of genetic and proteomic techniques, we are searching for novel proteins which are involved in the targeting of proteins to the proteasome during spermatogenesis in D. melanogaster testes, and are therefore involved in cell death.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 利用遗传学和蛋白质组学相结合的技术，我们正在寻找新的蛋白质，这些蛋白质在精子发生过程中参与蛋白质靶向蛋白酶体。黑腹睾丸，并因此参与细胞死亡。