TARGETING OF PROTEINS TO THE PROTEASOME DURING SPERMATOGENESIS

精子发生过程中蛋白质靶向蛋白酶体

• 批准号: 8361537
• 负责人: HERMANN STELLER
• 金额: $ 0.13万
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361537
• 关键词: Cell Death; Funding; Genetic; Grant; National Center for Research Resources; Principal Investigator; Proteins; Proteomics; Research; Research Infrastructure; Resources; Source; Spermatogenesis; Techniques; Testis; United States National Institutes of Health; cost; macromolecule; multicatalytic endopeptidase complex; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Using a combination of genetic and proteomic techniques, we are searching for novel proteins which are involved in the targeting of proteins to the proteasome during spermatogenesis in D. melanogaster testes, and are therefore involved in cell death.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 使用遗传学和蛋白质组学技术的组合，我们正在寻找新型蛋白质，这些蛋白质与蛋白质蛋白靶向蛋白质蛋白在蛋白酶体中靶向蛋白酶体，在甲状腺菌属d. melanogaster睾丸中，并参与细胞死亡。