FMRI OF PAIN MODULATION BY COGNITIVE BEHAVIORAL STRATEGIES

通过认知行为策略调节疼痛的 FMRI

• 批准号: 7722933
• 负责人: James Lawrence
• 金额: $ 0.28万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7722933
• 关键词: Amygdaloid structure; Area; Attention; Behavior; Behavioral; Biological Neural Networks; Cognitive; Computer Retrieval of Information on Scientific Projects Database; Funding; Goals; Grant; Hippocampus (Brain); Institution; Lead; Pain; Patients; Prefrontal Cortex; Recruitment Activity; Research; Research Personnel; Resources; Source; Structure; Techniques; Training; United States National Institutes of Health; chronic pain; cognitive modulation of pain; executive function; relating to nervous system

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cognitive behavioral strategies (CBS) are used to help chronic pain patients control their level of pain. The goal of this study is to distinguish the neural correlates of two different cognitive strategies: external focus of attention and reappraisal. These techniques were selected as they involve distinct behaviors and so are hypothesized to recruit distinct neural networks. External focus of attention was expected to evoke activity in areas involved in executive function (e.g. prefrontal cortex). Reappraisal was anticipated to recruit limbic structures (e.g. amygdala, hippocampus). Both techniques are effective in reducing pain and so are anticipated to exert influences on common areas of the pain matrix. n this may lead to more effective and efficient training.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 认知行为策略（CBS）被用来帮助慢性疼痛患者控制他们的疼痛水平。本研究的目的是区分两种不同的认知策略的神经相关：外部注意和重新评价。之所以选择这些技术，是因为它们涉及不同的行为，因此被假设为招募不同的神经网络。外部注意力的集中预计会引起与执行功能相关的区域（例如前额叶皮质）的活动。预期重新评估会招募边缘系统结构（例如杏仁核、海马体）。这两种技术都能有效减轻疼痛，因此预计会对疼痛矩阵的共同区域产生影响。这可能会导致更有效和更高效的培训。