COURSEWORK GRANT: COMPUTATIONAL MOLECULAR BIOLOGY AND GENOMICS

课程补助金：计算分子生物学和基因组学

• 批准号: 7723141
• 负责人: MARIE D DURAND
• 金额: $ 0.05万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723141
• 关键词: Algorithms; Computational Molecular Biology; Computer Retrieval of Information on Scientific Projects Database; Databases; Funding; Genes; Genomics; Grant; Institution; Methods; Molecular Biology; Molecular Models; Phylogeny; Research; Research Personnel; Resources; Sequence Alignment; Source; United States National Institutes of Health; abstracting; heuristics; lectures; markov model; programs; reconstruction

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Keywords: molecular biology, genomics Abstract: An advanced introduction to computational molecular biology, using an applied algorithms approach. The course will sruvey established algorithmic methods, including pairwise sequence alignment and dynamic programming, multiple sequence alignment, fast database search heuristics, hidden Markov models for molecular motifs, phylogeny reconstruction and gene finding. We will explore emerging computational problems in genomics through special topics lectures and course projects.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 关键词： 分子生物学、基因组学 抽象的： 计算分子生物学的高级介绍，使用 应用算法方法。该课程将建立 算法方法，包括成对序列比对和动态 编程、多序列比对、快速数据库搜索启发式、 用于分子基序、系统发育重建和 基因寻找。我们将探索基因组学中新出现的计算问题 通过专题讲座和课程项目。