COURSEWORK GRANT: COMPUTATIONAL MOLECULAR BIOLOGY AND GENOMICS

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 保留字： 分子生物学、基因组学 摘要： 一个先进的介绍计算分子生物学，使用 应用算法的方法。威尔·斯鲁维建立的课程 算法方法，包括成对序列比对和动态 编程，多序列比对，快速数据库搜索， 隐马尔可夫模型的分子模体，同源重建， 基因发现我们将探讨基因组学中新出现的计算问题 通过专题讲座和课程项目。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Keywords: molecular biology, genomics Abstract: An advanced introduction to computational molecular biology, using an applied algorithms approach. The course will sruvey established algorithmic methods, including pairwise sequence alignment and dynamic programming, multiple sequence alignment, fast database search heuristics, hidden Markov models for molecular motifs, phylogeny reconstruction and gene finding. We will explore emerging computational problems in genomics through special topics lectures and course projects.