COURSEWORK GRANT: COMPUTATIONAL MOLECULAR BIOLOGY AND GENOMICS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 关键词： 分子生物学、基因组学 摘要： 计算分子生物学的高级介绍，使用 应用算法方法。这门课将很快建立起来 算法方法，包括成对序列比对和动态比对 编程、多序列比对、快速数据库搜索启发式 分子基序的隐马尔可夫模型、系统发育重建和 基因发现。我们将探索基因组学中新出现的计算问题 通过专题讲座和课程项目。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Keywords: molecular biology, genomics Abstract: An advanced introduction to computational molecular biology, using an applied algorithms approach. The course will sruvey established algorithmic methods, including pairwise sequence alignment and dynamic programming, multiple sequence alignment, fast database search heuristics, hidden Markov models for molecular motifs, phylogeny reconstruction and gene finding. We will explore emerging computational problems in genomics through special topics lectures and course projects.