Identification of host genetic profiles to combat gastric cancer incidence

胃癌仍然是世界范围内痛苦和死亡的主要原因。虽然幽门螺杆菌被认为是胃癌的一个非常重要的风险因素，但包括受试者的基因构成和环境因素在内的其他因素也起着关键作用。因此，我们的目标是确定与不同人群中胃癌风险增加相关的特定先天基因变化，以便对受试者进行这些遗传生物标志物的筛查。

Stomach cancer remains a major cause of suffering and death worldwide. While the bacterium Helicobacter pylori is known to be a very important risk factor for stomach cancer, other factors including a subject’s genetic makeup and environmental factors also play a pivotal role. Thus, we aim to identify specific innate genetic changes that are associated with increased risk of stomach cancer across different populations so that subjects can be screened for these genetic biomarkers.