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3-D ORGANIZATION OF GENE EXPRESSION

3-D ORGANIZATION OF GENE EXPRESSION
基因表达的 3D 组织
批准号：
7722404
负责人：
DAVID L SPECTOR
金额：
$1.56万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-05-01 至 2009-04-30
来源：
https://reporter.nih.gov/project-details/7722404
关键词：
3-DimensionalChromatin StructureCollaborationsComputer Retrieval of Information on Scientific Projects DatabaseElectron MicroscopeFundingGene ExpressionGenetic TranscriptionGoalsGrantImageInstitutionLifeMorphologyNucleoplasmResearchResearch PersonnelResourcesSiteSourceSystemTechniquesTranscriptional ActivationUnited States National Institutes of Healthmessenger ribonucleoproteintomography

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Our goal is to investigate the chromatin structure during activation of transcription and to examine mRNP morphology at the transcription site and in the nucleoplasm using tetracysteine-biarsenical probes, correlated live imaging, and electron microscope tomography. The application and adaptation of these techniques to our system will be developed in collaboration with NCMIR/UCSD.
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海外基金