3-D ORGANIZATION OF GENE EXPRESSION
3-D ORGANIZATION OF GENE EXPRESSION
批准号:
7957595
负责人:
DAVID L SPECTOR
金额:
$2.49万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-06-15 至 2010-03-31
关键词:
3-DimensionalChromatin StructureCollaborationsComputer Retrieval of Information on Scientific Projects DatabaseElectron MicroscopeFundingGene ExpressionGenetic TranscriptionGoalsGrantImageImage AnalysisInstitutionLifeMorphologyNucleoplasmResearchResearch PersonnelResourcesSiteSourceSystemTechniquesTranscriptional ActivationUnited States National Institutes of Healthmessenger ribonucleoproteintomography
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
我们的目标是研究转录激活过程中的染色质结构,并使用四半胱氨酸-二砷探针、相关的实时成像和电子显微镜断层扫描来检查转录部位和核质中mRNP的形态。这些技术在我们的系统中的应用和改编将与NCMIR/UCSD合作开发。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Our goal is to investigate the chromatin structure during activation of transcription and to examine mRNP morphology at the transcription site and in the nucleoplasm using tetracysteine-biarsenical probes, correlated live imaging, and electron microscope tomography. The application and adaptation of these techniques to our system will be developed in collaboration with NCMIR/UCSD.
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会议论文
Probing the Function of Long Non-Coding RNAs in Differentiation
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批准号:10447087
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项目类别:
-
资助金额:$76.8万
-
财政年份:2019
-
负责人:DAVID L SPECTOR
-
依托单位:
Probing the Function of Long Non-Coding RNAs in Differentiation
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批准号:10224246
-
项目类别:
-
资助金额:$76.8万
-
财政年份:2019
-
负责人:DAVID L SPECTOR
-
依托单位:
Probing the Function of Long Non-Coding RNAs in Differentiation
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批准号:10653269
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项目类别:
-
资助金额:$76.8万
-
财政年份:2019
-
负责人:DAVID L SPECTOR
-
依托单位:
Project 3
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批准号:8744319
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项目类别:
-
资助金额:$42.22万
-
财政年份:2013
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负责人:DAVID L SPECTOR
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依托单位:
Long Nuclear-Retained Non-Coding RNAs and Cancer
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批准号:8234412
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项目类别:
-
资助金额:$43.22万
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财政年份:2012
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负责人:DAVID L SPECTOR
-
依托单位:
Spatial Organization of Gene Expressoin
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批准号:7988882
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项目类别:
-
资助金额:$9.51万
-
财政年份:2009
-
负责人:DAVID L SPECTOR
-
依托单位:
3-D ORGANIZATION OF GENE EXPRESSION
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批准号:7722404
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项目类别:
-
资助金额:$1.56万
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财政年份:2008
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负责人:DAVID L SPECTOR
-
依托单位:
3-D ORGANIZATION OF GENE EXPRESSION
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批准号:7601031
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项目类别:
-
资助金额:$1.09万
-
财政年份:2007
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负责人:DAVID L SPECTOR
-
依托单位:
3-D ORGANIZATION OF GENE EXPRESSION
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批准号:7358078
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项目类别:
-
资助金额:$0.81万
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财政年份:2006
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负责人:DAVID L SPECTOR
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依托单位:
PERKIN ELMER ULTRAVIEW LIVE CELL IMAGING SYSTEM: GENE EXPRESSION
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批准号:7166464
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项目类别:
-
资助金额:$11.3万
-
财政年份:2005
-
负责人:DAVID L SPECTOR
-
依托单位:
PERKIN ELMER ULTRAVIEW LIVE CELL IMAGING SYSTEM: CANCER
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批准号:7166462
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项目类别:
-
资助金额:$13.56万
-
财政年份:2005
-
负责人:DAVID L SPECTOR
-
依托单位:
PERKIN ELMER ULTRAVIEW LIVE CELL IMAGING SYSTEM: DNA REPLICATION, CELL BIOLOGY
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批准号:7166465
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项目类别:
-
资助金额:$13.56万
-
财政年份:2005
-
负责人:DAVID L SPECTOR
-
依托单位:
3-D ORGANIZATION OF GENE EXPRESSION
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批准号:7181376
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项目类别:
-
资助金额:$0.86万
-
财政年份:2005
-
负责人:DAVID L SPECTOR
-
依托单位:
PERKIN ELMER ULTRAVIEW LIVE CELL IMAGING SYSTEM: BREAST CANCER
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批准号:7166463
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项目类别:
-
资助金额:$6.78万
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财政年份:2005
-
负责人:DAVID L SPECTOR
-
依托单位:
Perkin Elmer UltraVIEW Live Cell Imaging System
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批准号:6877515
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项目类别:
-
资助金额:$45.21万
-
财政年份:2005
-
负责人:DAVID L SPECTOR
-
依托单位:
Kinetics of Chromatin Silencing in Live Mammalian Cells
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批准号:6946318
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项目类别:
-
资助金额:$30.9万
-
财政年份:2004
-
负责人:DAVID L SPECTOR
-
依托单位:
Kinetics of Chromatin Silencing in Live Mammalian Cells
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批准号:7115248
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项目类别:
-
资助金额:$31.57万
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财政年份:2004
-
负责人:DAVID L SPECTOR
-
依托单位:
Kinetics of Chromatin Silencing in Live Mammalian Cells
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批准号:6806759
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项目类别:
-
资助金额:$36.32万
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财政年份:2004
-
负责人:DAVID L SPECTOR
-
依托单位:
Kinetics of Chromatin Silencing in Live Mammalian Cells
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批准号:7274755
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项目类别:
-
资助金额:$31.09万
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财政年份:2004
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负责人:DAVID L SPECTOR
-
依托单位:
CORE--MICROSCOPY
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批准号:6617294
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项目类别:
-
资助金额:$7.89万
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财政年份:2002
-
负责人:DAVID L SPECTOR
-
依托单位:
海外基金