PROTEIN-PROTEIN INTERACTION BY SITE DIRECTED SPIN LABELED ESR

通过位点定向自旋标记 ESR 进行蛋白质-蛋白质相互作用

• 批准号: 7723984
• 负责人: ZHICHUN LIANG
• 金额: $ 0.33万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723984
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Data; Disease model; Funding; Grant; Institution; Least-Squares Analysis; Proteins; Research; Research Personnel; Resources; Services; Site; Source; Spin Labels; United States National Institutes of Health; base; programs; protein protein interaction

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. NLSL is a non linear least squares program for fitting CW spectra based on microscopically order but macroscopically disorder (MOMD) model. A service request was received from Mr. Francis Qufei Li for help on using our NLSL program to analyze his ESR data from a site directed spin labeled protein. The spectra were found to be in the slow motional region and consist of multiple components.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 NLSL是一种基于微观有序但宏观无序（MOMD）模型的非线性最小二乘程序。收到弗朗西斯李曲飞先生的服务请求，请求帮助使用我们的NLSL程序分析他的ESR数据，该数据来自定点自旋标记蛋白质。光谱被发现是在慢运动区，由多个组件。