STRUCTURAL STUDIES OF PROTEINS FROM HYPERTHERMOHILIC VIRUSES

高温病毒蛋白质的结构研究

• 批准号: 7721260
• 负责人: CHARLES MARTIN LAWRENCE
• 金额: $ 0.7万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-15 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7721260
• 关键词: Blast Cell; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Homologous Gene; Institution; Proteins; Research; Research Personnel; Resources; Source; Structure; United States National Institutes of Health; Viral Proteins; Virus; Work; beamline; protein function; protein structure

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Work at the NE-CAT beamline was focused on determining the structure of the STIV viral protein B129. The function of this protein can not be determined by sequence similarity using BLAST searches, or by CD searches or threading. We anticipate, however, that the structure of the protein will allow us to identify structural homologs, and thus to formulate a testable hypothesis regarding its function.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 在NE-CAT梁线上的工作集中在确定stiv病毒蛋白B129的结构上。 该蛋白质的功能无法通过使用BLAST搜索或CD搜索或螺纹来确定序列相似性。 但是，我们预计蛋白质的结构将使我们能够识别结构同源物，从而制定有关其功能的可检验假设。