Genetic Analysis of Molecular Interactions in Coronavirus Replication

冠状病毒复制中分子相互作用的遗传分析

• 批准号: 8102329
• 负责人: Paul Scott Masters
• 金额: $ 53.6万
• 依托单位: WADSWORTH CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8102329
• 关键词: Animals; Antiviral Agents; Binding; Biochemical; Biological; Birds; Cells; Characteristics; Chimera organism; Complex; Coronavirus; Coronavirus Infections; Coronavirus nucleocapsid protein; Coupled; Discipline; Disease; Dissection; E protein; Enteral; Family; Gene Deletion; Gene Expression; Genetic; Genetic Recombination; Genetic Transcription; Genome; Genomics; Goals; Human; Infectious Agent; Investigation; Knowledge; Laboratories; Learning; Life Cycle Stages; Link; Maps; Membrane Proteins; Methodology; Methods; Molecular; Molecular Biology; Morphogenesis; Murine hepatitis virus; Mutation; N Domain; Neurologic; Nucleocapsid; Participant; Phase; Phosphorylation; Play; Population; Process; Property; Prophylactic treatment; Proteins; RNA; RNA Viruses; RNA chemical synthesis; RNA-Protein Interaction; Role; Severe Acute Respiratory Syndrome; Signal Transduction; Site; Site-Directed Mutagenesis; Species Specificity; Structural Protein; System; Techniques; Tertiary Protein Structure; Time; Upper Respiratory Infections; Vaccine Design; Viral; Viral Genome; Viral Proteins; Virion; base; chemotherapy; complement system; env Gene Products; genetic analysis; human coronavirus; insight; multiple myeloma M Protein; mutant; positional cloning; prospective; protein E; protein structure function; prototype; public health relevance; respiratory; tool; viral RNA; virology; virus host interaction