Psychosocial Intervention for Children with IBD

IBD 儿童的心理社会干预

• 批准号: 7883260
• 负责人: Rona L. Levy
• 金额: $ 45.88万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-28 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7883260
• 关键词: Adolescent; Affect; Aftercare; Age; Anxiety; Attention; Attitude; Behavior; Belief; Caring; Child; Childhood; Chronic; Chronic Disease; Clinic Visits; Clinical Trials Design; Cognitive; Cognitive Therapy; Competence; Crohn' s disease; Data; Disease; Education; Exhibits; Family; Functional disorder; Gender; Goals; Hospitalization; Individual; Inflammatory Bowel Diseases; Intervention; Lead; Learning; Life; Measures; Medical; Medical History; Mental Depression; Modeling; Operative Surgical Procedures; Pain; Parents; Participant; Patients; Process; Psychological adjustment; Psychosocial Factor; Quality of life; Randomized; Randomized Controlled Trials; Recruitment Activity; Relaxation; Reporting; Research; Schools; Series; Severity of illness; Sick Role; Stress; Symptoms; Testing; Ulcerative Colitis; Visit; base; coping; demographics; disability; follow-up; functional disability; gastrointestinal; gastrointestinal symptom; health care service utilization; improved; innovation; interest; model development; primary outcome; psychosocial; response; skills; social; stress management; stressor; treatment effect; trial comparing

DESCRIPTION (provided by applicant): Inflammatory Bowel Disease (Crohn's and ulcerative colitis; IBD), a serious medical condition that affects children and adolescents, is often associated with high rates of health care utilization and disability, including school absence. While psychosocial factors are not believed to cause IBD, research suggests they may increase illness-related dysfunction. Prior studies from our group suggest that response to chronic illness is, in part, acquired during childhood through social learning processes and may be modified with psychosocial interventions. Although encouraging results of such interventions have been seen in patients with less severe conditions, well-designed trials of such interventions for children with IBD are lacking. The aim of the proposed study is to conduct a randomized controlled trial comparing social learning and cognitive behavior therapy (SLCBT) to an education and support condition (ES). 180 children with IBD will be recruited and followed for 12 months. It is hypothesized that SLCBT participants, compared to those in the ES condition, will, at one-year follow-up 1) exhibit greater decreases in IBD symptoms, medical visits for IBD, and functional disability, and greater increases in quality of life; 2) demonstrate greater use of cognitive coping, relaxation and stress management skills, and their parents will demonstrate greater reductions in maladaptive responses to illness behavior; and 3) exhibit greater reductions in anxiety, depression, and somatization. Secondary objectives are to investigate whether other variables, e.g., child age, gender, medical care and psychosocial variables such as social and academic competence, moderate treatment effects, and explore differences between the two groups in hospitalizations and surgeries for IBD, as well as general illness behavior. Data on children's symptoms, illness behaviors, functional disability, health care utilization, parental responses to children's illness behavior, beliefs regarding pain, and life stressors will be collected at baseline, post-treatment, and 3, 6, and 12 months post-treatment from parents and children. Results may lead to innovative interventions for IBD and other chronic childhood medical conditions.

描述（由申请人提供）：炎症性肠病（克罗恩病和溃疡性结肠炎; IBD）是一种影响儿童和青少年的严重疾病，通常与高医疗保健利用率和残疾率相关，包括缺课。虽然心理社会因素不被认为是导致IBD的原因，但研究表明它们可能会增加疾病相关的功能障碍。我们小组先前的研究表明，对慢性疾病的反应部分是在儿童时期通过社会学习过程获得的，并且可以通过心理干预进行修改。虽然在病情不太严重的患者中已经看到了这种干预措施的令人鼓舞的结果，但缺乏针对IBD儿童的这种干预措施的精心设计的试验。该研究的目的是进行一项随机对照试验，比较社会学习和认知行为疗法（SLCBT）与教育和支持条件（ES）。将招募180名IBD儿童并随访12个月。假设SLCBT参与者与ES条件下的参与者相比，在一年随访时，1）IBD症状、IBD就诊和功能障碍的减少更大，生活质量的增加更大; 2）表现出更多的认知应对、放松和压力管理技能，他们的父母将表现出对疾病行为的适应不良反应的减少更大;和3）表现出焦虑、抑郁和躯体化的更大降低。次要目的是调查其他变量，例如，儿童年龄，性别，医疗和社会心理变量，如社会和学术能力，中度治疗效果，并探讨两组之间的差异，住院和手术IBD，以及一般疾病行为。将在基线、治疗后和治疗后3、6和12个月从父母和儿童中收集有关儿童症状、疾病行为、功能残疾、医疗保健利用、父母对儿童疾病行为的反应、关于疼痛的信念和生活压力源的数据。研究结果可能会导致创新的干预IBD和其他慢性儿童疾病。