Randomized controlled trial of an internet-based prevention intervention for young children at-risk for functional abdominal pain
针对有功能性腹痛风险的幼儿进行基于互联网的预防干预的随机对照试验
基本信息
- 批准号:10608073
- 负责人:
- 金额:$ 66.61万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-04-11 至 2027-03-31
- 项目状态:未结题
- 来源:
- 关键词:AbdomenAbdominal PainAffectAgeAnatomyAnxietyAttentionBehaviorChildChild HealthChild RearingChild health careChildhoodCognitive TherapyCost SavingsDevelopmentDiagnosisEducationEnvironmentEsthesiaExposure toFamilyFamily health statusFutureGeneticHealthHealth Care CostsHealth Care VisitHealth ExpendituresInflammatoryInfluentialsInternetInterventionIrritable Bowel SyndromeLinkMediatingMental HealthMetabolismModelingMothersNeoplastic ProcessesNeurobiologyOnline SystemsOutcomePainPain DisorderParentsParticipantPatient RecruitmentsPopulations at RiskPreventiveProceduresQuality of lifeRandomized, Controlled TrialsReactionRecurrent painReportingResearchResearch DesignResourcesRiskRisk FactorsRisk ReductionSchoolsSeveritiesSick RoleSocial supportStressSymptomsTechnologyTestingTherapeutic InterventionTrainingWorkattentional controlchronic abdominal painchronic painchronic painful conditiondigital platformdisabilityearly childhoodefficacy evaluationefficacy testingemotional distressexperiencefollow-upgastrointestinal symptomhealth care service utilizationhealth related quality of lifehigh riskimprovedinterestintergenerationaloffspringpain symptomphysical conditioningpost interventionpreferencepreventpreventive interventionprimary outcomeprotective behaviorprotective factorspsychologicpsychosocialrecruitresponsesecondary outcomesocialsocial learningsocial mediatransmission processtreatment effecttwo-arm study
项目摘要
PROJECT SUMMARY
Exposure to a parent with chronic pain in childhood is one key risk factor for pain and adverse mental and
physical health outcomes among children. In particular, having a parent with Irritable Bowel Syndrome (IBS),
an idiopathic chronic abdominal pain disorder, places children at 2x greater risk for developing an abdominal
pain disorder. Our own research has demonstrated that pain-specific social learning is highly influential in this
intergenerational transmission. However, there is essentially no previous research that has attempted to
intervene with parents to prevent illness behaviors in early childhood, when these illness behaviors often
emerge and become established. Our team has developed and tested social learning and cognitive behavioral
therapy (SLCBT) interventions to change parental behaviors and modeling in order to reduce children’s illness
behaviors. We hypothesize that SLCBT can be modified toward a preventive focus for parents with IBS who
have young asymptomatic children, ages 4-6 years, in order to reduce risk factors (anxiety, catastrophizing,
parenting stress) and increase protective factors (positive affect, social support), resulting in fewer abdominal
pain symptoms in children, reduced health care utilization, and less health-related disability. Therefore, the
objective of the current application is to test the efficacy of an early preventive intervention targeting parents
with IBS whose young children are thus at higher risk for developing illness behavior and subsequently a
diagnosis of a chronic abdominal pain disorder. To enhance potential for scalability and dissemination, and
meet parental preferences, we propose delivering the intervention via the internet through approaches our
team has successfully used with other psychosocial pain interventions. The study design is a randomized
controlled trial with parallel 1:1 assignment to two study arms, 1) attention education control, and 2) SLCBT
prevention intervention. We aim to recruit 460 parents with IBS who have young children ages 4-6 years.
Participants will be assessed at baseline, 6-week (immediate post-intervention), 6-month, 12-month, and 18-
month follow-up periods. All study procedures will be conducted remotely using digital platforms and web-
based technologies. Social media ads will be used to advertise the study and recruit participants. The primary
outcome is change in parental solicitous/protective behaviors. Secondary outcomes include parent risk and
protective factors and child health and symptom outcomes. We will determine cost savings of implementing
this preventive intervention on health care expenditures and resource utilization over 18 months. The proposed
study will be the first to evaluate the potential benefit of an early preventive psychosocial intervention
specifically for children at risk for a common pediatric pain condition. If successful, this study has high potential
impact to provide a model for a preventive intervention for a wide range of pediatric health problems which can
impact functioning beyond childhood in which parental responses are influencing factors.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Rona L. Levy其他文献
36 FACTORS ASSOCIATED WITH ADHERENCE TO A LOW FERMENTABLE CARBOHYDRATE DIET IN CHILDREN WITH IRRITABLE BOWEL SYNDROME
- DOI:
10.1016/s0016-5085(21)00773-3 - 发表时间:
2021-05-01 - 期刊:
- 影响因子:
- 作者:
Rachel B. Tenenbaum;Danita I. Czyzewski;Ann R. McMeans;Vishnu Narayana;Rona L. Levy;Robert J. Shulman;Bruno P. Chumpitazi;Mariella M. Self - 通讯作者:
Mariella M. Self
Tu1775 SLEEP PARASOMNIAS ARE ASSOCIATED WITH AUTONOMIC NERVOUS SYSTEM DYSFUNCTION IN CHILDREN WITH FUNCTIONAL ABDOMINAL PAIN DISORDERS
- DOI:
10.1016/s0016-5085(20)33563-0 - 发表时间:
2020-05-01 - 期刊:
- 影响因子:
- 作者:
Miranda A. van Tilburg;Robert Burr;Jennifer Cowie-Jansen;Mariella M. Self;Margaret Heitkemper;Joan M. Romano;Rona L. Levy;Robert J. Shulman - 通讯作者:
Robert J. Shulman
The comparative cost of IBS in an HMO
- DOI:
10.1016/s0016-5085(00)83703-8 - 发表时间:
2000-04-01 - 期刊:
- 影响因子:
- 作者:
Rona L. Levy;Paul Stang;Michael VonKorff;Andrew D. Feld;Priti Jhingrin - 通讯作者:
Priti Jhingrin
Sa1637 IBS MOTHERS IN JAPAN WHO HAVE CHILDREN WITH RECURRENT ABDOMINAL PAIN (RAP) ARE MORE LIKELY TO DISCOURAGE RATHER THAN TO ENCOURAGE CHILD ILLNESS BEHAVIOR.
- DOI:
10.1016/s0016-5085(20)31603-6 - 发表时间:
2020-05-01 - 期刊:
- 影响因子:
- 作者:
Motoyori Kanazawa;Daiki Abukawa;Nami Honda;Shunichi Funakoshi;Fumihiko Kakuta;William E. Whitehead;Lynn Walker;Rona L. Levy;Shin Fukudo - 通讯作者:
Shin Fukudo
Sa1730 RELATIONSHIP BETWEEN FUNCTIONAL ABDOMINAL PAIN, PAINASSOCIATED IMPAIRMENT, AND PSYCHOLOGICAL FACTORS VARY BASED ON CHILDREN'S RACE AND ETHNICITY
- DOI:
10.1016/s0016-5085(24)01615-9 - 发表时间:
2024-05-18 - 期刊:
- 影响因子:
- 作者:
Katherine Lamparyk;Tasha Murphy;Kendra Kamp;Rona L. Levy;Robert J. Shulman;Miranda A. van Tilburg - 通讯作者:
Miranda A. van Tilburg
Rona L. Levy的其他文献
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{{ truncateString('Rona L. Levy', 18)}}的其他基金
Randomized controlled trial of an internet-based prevention intervention for young children at-risk for functional abdominal pain
针对有功能性腹痛风险的幼儿进行基于互联网的预防干预的随机对照试验
- 批准号:
10387725 - 财政年份:2022
- 资助金额:
$ 66.61万 - 项目类别:
DO BIOMARKERS PREDICT RESPONSE TO A PEDIATRIC CHRONIC PAIN SYMPTOM MANAGEMENT PROGRAM?
生物标志物可以预测儿科慢性疼痛症状管理计划的反应吗?
- 批准号:
10594032 - 财政年份:2018
- 资助金额:
$ 66.61万 - 项目类别:
DO BIOMARKERS PREDICT RESPONSE TO A PEDIATRIC CHRONIC PAIN SYMPTOM MANAGEMENT PROGRAM?
生物标志物可以预测儿科慢性疼痛症状管理计划的反应吗?
- 批准号:
9899324 - 财政年份:2018
- 资助金额:
$ 66.61万 - 项目类别:
Healthy Homes/Healthy Kids: Pediatric Primary Care-based Obesity Prevention
健康家庭/健康儿童:基于儿科初级保健的肥胖预防
- 批准号:
8539595 - 财政年份:2009
- 资助金额:
$ 66.61万 - 项目类别:
Healthy Homes/Healthy Kids: Pediatric Primary Care-based Obesity Prevention
健康家庭/健康儿童:基于儿科初级保健的肥胖预防
- 批准号:
7925829 - 财政年份:2009
- 资助金额:
$ 66.61万 - 项目类别:
Healthy Homes/Healthy Kids: Pediatric Primary Care-based Obesity Prevention
健康家庭/健康儿童:基于儿科初级保健的肥胖预防
- 批准号:
8325143 - 财政年份:2009
- 资助金额:
$ 66.61万 - 项目类别:
Healthy Homes/Healthy Kids: Pediatric Primary Care-based Obesity Prevention
健康家庭/健康儿童:基于儿科初级保健的肥胖预防
- 批准号:
8135997 - 财政年份:2009
- 资助金额:
$ 66.61万 - 项目类别:
Healthy Homes/Healthy Kids: Pediatric Primary Care-based Obesity Prevention
健康家庭/健康儿童:基于儿科初级保健的肥胖预防
- 批准号:
8726565 - 财政年份:2009
- 资助金额:
$ 66.61万 - 项目类别:
Healthy Homes/Healthy Kids: Pediatric Primary Care-based Obesity Prevention
健康家庭/健康儿童:基于儿科初级保健的肥胖预防
- 批准号:
7712821 - 财政年份:2009
- 资助金额:
$ 66.61万 - 项目类别:
Psychosocial Intervention for Children with IBD
IBD 儿童的心理社会干预
- 批准号:
7883260 - 财政年份:2007
- 资助金额:
$ 66.61万 - 项目类别:
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针对有功能性腹痛风险的幼儿进行基于互联网的预防干预的随机对照试验
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