MOREHOUSE-EMORY PARTNERSHIP TO REDUCE CV DISPARITIES ? AIM II

莫尔豪斯-埃默里大学合作减少简历差异？

• 批准号: 8173618
• 负责人: PRISCILLA E PEMU
• 金额: $ 12.9万
• 依托单位: MOREHOUSE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173618
• 关键词: Address; African American; Awareness; Bispecific Antibody 2B1; Caring; Cholesterol; Clinical; Clinical Research; Communities; Community Physician; Computer Retrieval of Information on Scientific Projects Database; Data Collection; Diagnosis; Diet; Dietary Practices; Education; Educational Intervention; Exercise Tolerance; Exhibits; Feedback; Focus Groups; Food; Funding; Grant; Guidelines; Health behavior; High Density Lipoproteins; Hour; Inflammatory; Institution; Insulin; Intervention; Metabolic; Metabolic syndrome; Outcome; Participant; Patients; Pattern; Performance; Phase; Physicians; Pilot Projects; Provider; Psyche structure; Psychosocial Factor; Questionnaires; Randomized; Records; Research; Research Personnel; Resources; Risk Factors; SF-36; Self Efficacy; Self Management; Serum; Social support; Source; Staging; Stress; Structure; Treadmill Tests; Treatment outcome; United States National Institutes of Health; Weight; base; bone; depressive symptoms; expectation; experience; fasting glucose; follow-up; health related quality of life; improved; lifestyle intervention; lipoprotein triglyceride; medication compliance; primary care setting; standardized care; treatment as usual

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. he specific aims of the original proposal were unmodified and remain as follows: Specific Aim 2: To promote physician awareness and patient lifestyle interventions to enhance treatment and outcomes of CV risk factors associated with Metabolic Syndrome in hypertensive African Americans. Specific Aim 2a: To determine the baseline state of awareness, treatment and control of the Metabolic Syndrome among community based practitioners, and provide a physician feedback and education intervention on provider diagnosis and treatment of CV risk factors associated with the Metabolic Syndrome in hypertensive African Americans. We will describe practice patterns in primary care settings, and compare the percentages of hypertensive patients who are treated with JCN7 and ATPIII guidelines and assessed for the Metabolic Syndrome before and after structured performance feedback and education(audit feedback). Specific Aim 2b: To develop and evaluate the effects of a culturally sensitive self management lifestyle intervention (LSI) on health behaviors, clinical outcomes and psychosocial factors in hypertensive AA with CV risk factors associated with the Metabolic Syndrome. 2b1. Primary aim To determine if participants who receive the LSI intervention demonstrate improved health behaviors over participants randomized to usual care (UC) as exhibited by: increased exercise tolerance test (treadmill), increased PA levels (Metabolic Syndrome-h/week from CAPS Questionnaire); improved dietary patterns (Block Questionnaire; 3 day food records), and improved medication compliance (Hill-Bone Questionnaire). 2b2. Secondary aim: To determine if participants who receive the LSI demonstrate improved clinical outcomes over those randomized to UC as exhibited by: lower systolic and diastolic BP, lower weight, improved serum total cholesterol, high density lipoproteins, and triglyceride levels, and improved metabolic and inflammatory profile (fasting glucose, 2 hour glucose, fasting insulin, HOMA, CRP). 2b3. Tertiary aim: To determine if participants who receive the LSI experience improved health related quality of life (HRQOL) and psychosocial factors over those receiving UC as exhibited by improved overall physical and mental functioning (SF-36), lower perceived stress, lower depressive symptoms, increased social support, increased diet and PA self efficacy, and increased stage of change for PA. We proposed to carry out the study in three phases. Phase I involves a detailed assessment of hypertensive care among the Community Physician Network (CPN) practices with efforts made to standardize care. Specific aim 2a is addressed in phase I. In phase II, which addresses aim 2b ( "develop and evaluate a culturally sensitive self-management lifestyle intervention on health behaviors") focus groups to assess concordance of planned intervention to expectations and acceptance, and a pilot study were conducted, Phase III is the clinical study involving recruitment and randomization of patients to usual care or the lifestyle intervention with baseline and follow-up data collection and analysis.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 原始提案的具体目的是未经修改的，并且保持如下： 具体目标2：促进医师意识和患者生活方式干预措施，以增强与高血压非裔美国人中代谢综合征相关的简历危险因素的治疗和结果。 具体目的2a：确定社区从业人员之间对代谢综合征的意识，治疗和控制的基线状态，并就提供者诊断和治疗与高血压非裔美国人的代谢综合征相关的提供者诊断和治疗的医师反馈和教育干预。我们将描述初级保健环境中的实践模式，并比较接受JCN7和ATPIII指南治疗的高血压患者的百分比，并在结构化绩效反馈和教育（审计反馈）之前和之后评估了代谢综合征的百分比。 具体目标2b：开发和评估具有文化敏感的自我管理生活方式干预（LSI）对高血压AA健康行为，临床结果和心理社会因素的影响，其与代谢综合征相关的CV风险因素。 2B1。确定接受LSI干预的参与者的主要目的是否表现出与随机分配给常规护理（UC）（UC）的健康行为的改善，如：增加运动耐受性测试（Treadmill），PA水平升高（CAPS问卷中的代谢综合征/周/周）；改进的饮食模式（块问卷； 3天的食物记录）和改进的药物合规性（山骨头问卷）。 2b2。 Secondary aim: To determine if participants who receive the LSI demonstrate improved clinical outcomes over those randomized to UC as exhibited by: lower systolic and diastolic BP, lower weight, improved serum total cholesterol, high density lipoproteins, and triglyceride levels, and improved metabolic and inflammatory profile (fasting glucose, 2 hour glucose, fasting insulin, HOMA, CRP). 2B3。第三级目的：确定接受LSI经验的参与者是否改善了与健康相关的生活质量（HRQOL）和社会心理因素，而接受UC的参与者是否通过改善的整体身体和精神功能（SF-36）表现出的那些接受UC的参与者（SF-36），较低的感知压力，较低的抑郁症状，较低的抑郁症状，较低的抑郁症状，增加的社交支持，饮食支持，饮食支持和PA自我效率和PA的阶段增加，并增加了PA的变化阶段。 我们提议分为三个阶段进行研究。第一阶段涉及对社区医师网络（CPN）实践中高血压护理的详细评估，并通过标准化护理进行了努力。在第一阶段中解决了具体目标2a，在第二阶段中解决了目标2b（“开发和评估对健康行为的文化敏感自我管理生活方式干预”）焦点小组，以评估计划的干预对期望和接受的一致性，并进行了试点研究，并进行了一项III，涉及对患者的临床研究和随机分析和随机分析或随机分析或随机分析或随机性和随机性和随机性和随机性和随机性和随机性而进行。