META HEALTH - AIM II

元健康 - AIM II

• 批准号: 7720626
• 负责人: PRISCILLA E PEMU
• 金额: $ 9.76万
• 依托单位: MOREHOUSE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7720626
• 关键词: African American; Awareness; Caring; Cholesterol; Clinical; Computer Retrieval of Information on Scientific Projects Database; Counseling; Diagnosis; Diet; Evaluation; Exercise Tolerance; Exhibits; Fasting; Focus Groups; Funding; Glucose; Grant; Health; Health behavior; High Density Lipoproteins; Hour; Inflammatory; Institution; Insulin; Intervention; Life Style; Metabolic; Metabolic syndrome; Outcome; Participant; Patients; Pattern; Physicians; Population; Primary Health Care; Protocols documentation; Provider; Psyche structure; Psychosocial Factor; Questionnaires; Randomized; Recommendation; Research; Research Personnel; Resources; Risk Factors; SF-36; Self Efficacy; Self Management; Serum; Social support; Source; Staging; Stress; Telephone; Treadmill Tests; Treatment outcome; United States National Institutes of Health; Upper arm; Week; Weight; bone; cysteine rich protein; depressive symptoms; design; experience; health related quality of life; improved; lifestyle intervention; lipoprotein triglyceride; medication compliance

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. That a culturally sensitive tailored lifestyle intevention will improve outcomes in African Americans with metabolic syndrome compared with usual care in a primary care ssetting. Specific Aims: To promote physician awareness and patient lifestyle interventions to enhance treatment and outcomes of CV risk factors associated with MetS in hypertensive African Americans. To develop and evaluate the effects of a culturally- sensitive self- management lifestyle intervention (LSI) on health behaviors, clinical outcomes and psychosocial factors in hypertensive AA with CV risk factors associated with the MetS. Primary outcome: To determine if participants who receive the LSI intervention demonstrate improved health behaviors over participants randomized to usual care (UC) as exhibited by: increased exercise tolerance test (treadmill), increased PA levels (Mets-h/week from modified Baeke Questionnaire); improved dietary patterns (Block Questionnaire), and improved medication compliance (Hill-Bone Questionnaire). 2b2. Secondary outcomes: To determine if participants who receive the LSI demonstrate improved clinical outcomes over those randomized to UC as exhibited by: lower systolic and diastolic BP, lower weight, improved serum total cholesterol, high density lipoproteins, and triglyceride levels, and improved metabolic and inflammatory profile (fasting glucose, two hour glucose, fasting insulin, HOMA, CRP). 2b3. Tertiary outcomes: To determine if participants who receive the LSI experience improved health- related quality of life (HRQOL) and psychosocial factors over those receiving UC as exhibited by improved overall physical and mental functioning (SF-36), lower perceived stress, lower depressive symptoms, increased social support, increased diet and PA self efficacy, and increased stage of change for PA. Experimental Protocol: Three separate focus groups with six-eight CPN patients diagnosed with the MetS will be conducted to determine acceptance of the content of the intervention and correspondence with the needs of the population, preferred styles of materials, perceived barriers/benefits of participating in the intervention, and perceived barriers/benefits for improved health behaviors. A two-arm, parallel-group, multi-center design will be used to randomize subjects within the CPN to usual care (UC) or the LSI intervention. Participants randomized to UC will receive usual care from their provider, and will be given a MetS resource folder consisting of information and healthy lifestyle recommendations. Participants randomized to the LSI group will receive UC plus six group sessions designed to improve PA, diet and medication compliance, followed by 10 phone counseling sessions by a CHW. Baseline, three, six and twelve month evaluations will be completed for both groups.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 与初级保健贫困相比，具有文化敏感的量身定制的生活方式的态度将改善代谢综合征的结果。 具体目的：促进医师意识和患者生活方式干预措施，以增强与高血压非裔美国人中与METS相关的简历危险因素的治疗和结果。 在高血压AA中，具有文化敏感的自我管理生活方式干预（LSI）对健康行为，临床结果和心理社会因素的影响和评估与大都会大都会大都会有关的CV风险因素的影响。 主要结果：确定接受LSI干预的参与者是否表现出比随机分配到常规护理（UC）的参与者的改善，如：增加运动耐受性测试（跑步机），PA水平升高（Mets-H/周的METS-H/周，来自修改后的Baeke Queitaire）；改进的饮食模式（块问卷）和改善的药物合规性（山骨头问卷）。 2b2。 Secondary outcomes: To determine if participants who receive the LSI demonstrate improved clinical outcomes over those randomized to UC as exhibited by: lower systolic and diastolic BP, lower weight, improved serum total cholesterol, high density lipoproteins, and triglyceride levels, and improved metabolic and inflammatory profile (fasting glucose, two hour glucose, fasting insulin, HOMA, CRP). 2B3。第三级结果：确定接受LSI经验的参与者是否改善了与健康相关的生活质量（HRQOL）和心理社会因素，而不是接受UC的患者，这是通过改善的整体身体和心理功能（SF-36）表现出的，较低感知的压力，较低的抑郁症状，较低的抑郁症状，较低的抑郁症状，社交支持的增加，饮食支持，增加饮食和PA自效率和PA自效和PA的阶段和PA的阶段增加。 实验方案：将进行三个独立的焦点小组，其中有六名CPN患者将进行诊断为METS的患者，以确定接受干预的含量以及与人口需求的含义，并与人口的需求，首选材料样式，参与干预的感知障碍/益处，以及参与干预的障碍以及感知的障碍/福利，以改善健康行为。两臂平行组的​​多中心设计将用于将CPN中的受试者随机化，以进行常规护理（UC）或LSI干预。随机分配给UC的参与者将从其提供商那里获得通常的护理，并将获得一个由信息和健康生活方式建议组成的Mets资源文件夹。随机分配到LSI组的参与者将获得UC加上六次小组会议，旨在提高PA，饮食和药物合规性，然后由CHW进行10次电话咨询课程。两组将完成基线，三个，六和十二个月的评估。