Autologous adult human mesenchymal stem cells: a neuroprotective therapy for multiple sclerosis

自体成人间充质干细胞：多发性硬化症的神经保护疗法

• 批准号: G0502107/1
• 负责人: Siddharthan Chandran
• 金额: $ 94.6万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0502107%2F1
• 关键词: Autologous; adult; human; mesenchymal; stem

MS is a disease where nerves and its insulation layer are damaged leading to symptoms. Over time the nerve damage accumulates leading to fixed and progressive disability in the vast majority of patients. Therapies for MS presently are limited only to partially reducing the frequency of individual attacks. There are no effective treatments to protect the nerves. This study is trying to explore whether stem cells taken from the patients bone marrow or skin could through a cell infusion (similar to blood transfusion) protect the nerves of the MS patient.

多发性硬化症是一种神经及其绝缘层受损并导致症状的疾病。随着时间的推移，神经损伤不断累积，导致绝大多数患者出现固定性和渐进性残疾。目前多发性硬化症的治疗仅限于部分减少个别发作的频率。没有有效的治疗方法来保护神经。本研究试图探讨从患者骨髓或皮肤中提取的干细胞是否可以通过细胞输注（类似于输血）来保护多发性硬化症患者的神经。