Community-based Hep B Intervention for Hmong Adults

针对苗族成人的社区乙肝干预

• 批准号: 7914083
• 负责人: Moon Shao-Chuang Chen
• 金额: $ 37.31万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7914083
• 关键词: Adult; Affect; Age; Aleurites; American; Area; Asian Americans; Asians; Awareness; Birds; California; Cambodia; Cancer Center; Cancer Control; Cancer Control Research; Characteristics; China; Chinese American; Commit; Communities; Control Groups; Country; Data; Diagnosis; Effectiveness; Effectiveness of Interventions; Elements; Ethnic group; Evaluation; Family; Farming environment; Female; Fostering; Goals; Government; Health; Health behavior; Helicobacter Infections; Hepatitis B; Hepatitis B Virus; Home environment; Human Herpesvirus 4; Incidence; Infection; Intervention; Interviewer; Knowledge; Korea; Korean American; Language; Laos; Learning; Letters; Life Style; Location; Longitudinal Studies; Malignant Neoplasms; Malignant neoplasm of liver; Measures; Medical Records; Methods; Modeling; Moon; National origin; Not Hispanic or Latino; Participant; Patient Self-Report; Peer Review; Population; Prevention; Primary carcinoma of the liver cells; Randomized; Randomized Controlled Trials; Reporting; Research; Research Design; Research Infrastructure; Research Personnel; Resources; Risk; Risk Factors; Role; Rural; Sample Size; Scientist; Seasons; Serologic tests; Southeastern Asia; Staging; Structure; Survival Rate; Techniques; Testing; Time; Training; Vietnam; Work; Writing; Yang; aged; base; cancer diagnosis; cancer risk; community intervention; design; effective intervention; experience; group intervention; literate; liver cancer prevention; male; malignant stomach neoplasm; migration; neoplasm registry; programs; research study

Unlike other ethnic groups who attribute their origin to a single country, Hmong Americans originate from the mountainous regions at the confluence of Vietnam, Cambodia, and Laos. The U.S. government resettled Hmong who escaped from Southeast Asia to California and the Midwest. At the time of migration, the Hmong were pre-literate, believed in animism, and were accustomed to an agrarian lifestyle. Our latest California data indicate that the age-adjusted male incidence rate for liver cancer for Hmong is 25.7/100,000 compared to 3.7/100,000 for non-Hispanic white males and 8.8/100,000 for female Hmong compared to 1.5/100,000 in non-Hispanic White females. The purpose of this study is to increase the hepatitis B serological testing for Hmong adults and secondarily to increase their knowledge levels of hepatitis B and liver cancer. Over the five year research tudy, we propose to: (1) measure the baseline proportion seroloically tested for hepatitis B [HBV] among Hmong, ages 18-64, in the Greater Sacramento Area; (2) Develop an intervention using lay health workers to promote serological testing for HBV and increase knowledge of HBV among Hmong adults; (3) Evaluate the effectiveness of the lay health worker intervention by conducting a randomized, controlled trial among Hmong adults aged 18-64 not previously tested for HBV; and (4) Characterize facilitating and impeding factors associated with serological testing for HBV among Hmong adults. To achieve these Aims, universitybased researchers will work collaboratively with Hmong bilingual interviewers, community leaders, and agencies in conducting a baseline assessment of serological testing among Hmong and follow with randomizing those who have not been serologically tested for HBV into intervention or control conditions. We shall use the Health Behavior Framework to guide our study and the lay health worker teams as the intervention agents . Intervention effectiveness will be based on the basis of self-reported serological testing rates that will be also verified through medical records check. We have detailed the training and evaluation of lay health workers and have incorporated rigorous safeguards to minimize contamination. As a consequence of this study, we expect data on the empirical effectiveness of a lay health worker intervention model for increasing serological testing for HBV and that the burden of HBV-induced liver cancer reduced.

与其他将其起源归因于一个国家的种族不同，苗族美国人起源于 越南，柬埔寨和老挝汇合处的山区地区。美国政府重新安置 苗族从东南亚逃到加利福尼亚和中西部。在迁移时， 苗族是预先识别的，相信万物有灵，并习惯了农业生活方式。我们的最新消息 加利福尼亚的数据表明，苗族肝癌的年龄调整后的男性发病率为25.7/100,000 相比之下，非西班牙裔白人男性为3.7/100,000，女性苗族为8.8/100,000 非西班牙裔白人女性的1.5/100,000。 这项研究的目的是增加肝炎成人的血清学测试和 其次是为了提高其B和肝癌的知识水平。在五年的研究中 tudy，我们建议：（1）测量对乙型肝炎的基线比例在 苗族，18-64岁，在大萨克拉曼多地区； （2）使用外行健康工作者进行干预 促进血清学测试HBV并增加苗族成年人中HBV的知识； （3）评估 外行卫生工作者干预的有效性通过在 以前未对HBV测试的18-64岁的苗族成年人； （4）表征促进和阻碍 苗族成年人中HBV的血清学测试相关的因素。为了实现这些目标，基于大学 研究人员将与苗族双语访调员，社区领袖和 对苗族进行血清学测试的基线评估的机构，然后 随机将未经过血清学测试的HBV进行干预或控制条件进行。 我们将使用健康行为框架来指导我们的研究和外行健康工作者团队 干预剂。干预有效性将基于自我报告的血清学测试 还将通过病历检查验证的费率。我们已经详细介绍了培训和评估 外行卫生工作者，并结合了严格的保障措施，以最大程度地减少污染。作为 这项研究的结果，我们期望外行卫生工作者干预的经验有效性数据 增加了HBV血清学测试的模型，HBV诱导的肝癌的负担减少了。