IDENTIFICATION OF PHOSPHORYLATION SITES ON GLUTAMATE RECEPTOR MGLUR5
IDENTIFICATION OF PHOSPHORYLATION SITES ON GLUTAMATE RECEPTOR MGLUR5
批准号:
7954097
负责人:
PAUL GREENGARD
金额:
$0.12万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-03-01 至 2010-02-28
关键词:
Computer Retrieval of Information on Scientific Projects DatabaseFundingGRM5 geneGlutamate ReceptorGrantInstitutionMass Spectrum AnalysisMetabotropic Glutamate ReceptorsPhosphorylation SiteResearchResearch PersonnelResourcesRoleSiteSourceUnited States National Institutes of Healthmacromoleculemutantnovelreceptor function
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
我们正在使用假设驱动的质谱学来确定代谢性谷氨酸受体mGluR5上的新的磷酸化位点。将构建特定磷酸化位点的突变体,以获得关于这些位点在受体功能上的作用的信息。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
we are using hypothesis-driven mass spectrometry to identify novel phosphorylation sites on the metabotropic glutamate receptor, mGluR5. Mutants of the specific sites of phopshorylation will be constructed to obtain information about the roles of these sites on the function of the receptor.
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会议论文
MECHANISMS FOR SELECTIVE REGULATION OF GAMMA-SECRETASE (AG09464-21A1 PROJ 2
-
批准号:8724095
-
项目类别:
-
资助金额:$57.67万
-
财政年份:2013
-
负责人:PAUL GREENGARD
-
依托单位:
MECHANISMS FOR SELECTIVE REGULATION OF GAMMA-SECRETASE (AG09464-21A1 PROJ 2
-
批准号:8735057
-
项目类别:
-
资助金额:$57.67万
-
财政年份:2013
-
负责人:PAUL GREENGARD
-
依托单位:
P2 - Role of mGluR5/CK1-CK2/DARPP-32 Pathway in Psychostimulant Effects
-
批准号:8334266
-
项目类别:
-
资助金额:$32.58万
-
财政年份:2011
-
负责人:PAUL GREENGARD
-
依托单位:
IDENTIFICATION OF PHOSPHORYLATION SITES ON GLUTAMATE RECEPTOR MGLUR5
-
批准号:8361517
-
项目类别:
-
资助金额:$0.13万
-
财政年份:2011
-
负责人:PAUL GREENGARD
-
依托单位:
Identification of Cell Type-Specific Actions of Antipsychotic Drugs
-
批准号:8151096
-
项目类别:
-
资助金额:$197.83万
-
财政年份:2010
-
负责人:PAUL GREENGARD
-
依托单位:
Identification of Cell Type-Specific Actions of Antipsychotic Drugs
-
批准号:8328723
-
项目类别:
-
资助金额:$198.0万
-
财政年份:2010
-
负责人:PAUL GREENGARD
-
依托单位:
Identification of Cell Type-Specific Actions of Antipsychotic Drugs
-
批准号:7939293
-
项目类别:
-
资助金额:$199.29万
-
财政年份:2010
-
负责人:PAUL GREENGARD
-
依托单位:
Identification of Cell Type-Specific Actions of Antipsychotic Drugs
-
批准号:8475657
-
项目类别:
-
资助金额:$190.08万
-
财政年份:2010
-
负责人:PAUL GREENGARD
-
依托单位:
Administrative Core
-
批准号:8150133
-
项目类别:
-
资助金额:$6.5万
-
财政年份:2010
-
负责人:PAUL GREENGARD
-
依托单位:
Striatal Cell-specific Analysis of the Molecular Mechanisms of Antipsychotic Drug
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批准号:8150110
-
项目类别:
-
资助金额:$26.0万
-
财政年份:2010
-
负责人:PAUL GREENGARD
-
依托单位:
IDENTIFICATION OF PHOSPHORYLATION SITES ON GLUTAMATE RECEPTOR MGLUR5
-
批准号:8169137
-
项目类别:
-
资助金额:$0.12万
-
财政年份:2010
-
负责人:PAUL GREENGARD
-
依托单位:
IDENTIFICATION OF PHOSPHORYLATION SITES ON GLUTAMATE RECEPTOR MGLUR5
-
批准号:7722242
-
项目类别:
-
资助金额:$0.11万
-
财政年份:2008
-
负责人:PAUL GREENGARD
-
依托单位:
ID & QUANTITATION OF PHOSPHORYLATION OF REGULATOR OF CALMODULIN SIGNALING
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批准号:7722226
-
项目类别:
-
资助金额:$0.11万
-
财政年份:2008
-
负责人:PAUL GREENGARD
-
依托单位:
Psychostimulants and Dendritic Spines
-
批准号:7513627
-
项目类别:
-
资助金额:$32.24万
-
财政年份:2007
-
负责人:PAUL GREENGARD
-
依托单位:
Project 1 - Greengard (pgs. 101 - 120)
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批准号:7551816
-
项目类别:
-
资助金额:$33.5万
-
财政年份:2007
-
负责人:PAUL GREENGARD
-
依托单位:
Project 2 - Heintz (pgs. 121 - 140)
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批准号:7551817
-
项目类别:
-
资助金额:$33.5万
-
财政年份:2007
-
负责人:PAUL GREENGARD
-
依托单位:
Project 4 - Nestler (pgs. 161 - 186)
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批准号:7551819
-
项目类别:
-
资助金额:$30.52万
-
财政年份:2007
-
负责人:PAUL GREENGARD
-
依托单位:
Project 5 - Surmeier (pgs. 187 - 204)
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批准号:7551820
-
项目类别:
-
资助金额:$29.05万
-
财政年份:2007
-
负责人:PAUL GREENGARD
-
依托单位:
Administrative Core
-
批准号:7513636
-
项目类别:
-
资助金额:$5.08万
-
财政年份:2007
-
负责人:PAUL GREENGARD
-
依托单位:
Molecular and Biochemical Core - Greengard (pgs. 236 - 251)
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批准号:7551822
-
项目类别:
-
资助金额:$20.94万
-
财政年份:2007
-
负责人:PAUL GREENGARD
-
依托单位:
海外基金