HPV Infection Among High-Risk Young Men in Puerto Rico

生殖器HPV感染是全球最常见的性传播疾病之一，其 高流行率还可能导致艾滋病毒传播风险的增加。虽然人乳头瘤病毒 感染与男性和女性的慢性疾病后遗症有因果关系 女性，对HPV感染和HPV的分布知之甚少 其中与艾滋病毒状况有关的亚型。了解流行率、分布、 而HIV+和HIV-个体中HPV亚型的一般来源是 对于了解HPV的长期健康后果很重要。内部研究人员 公共卫生医学院全球卫生研究中心 波多黎各科学校园，与最大的公共资助的STI合作 岛上的诊所(传播性传播的拉丁美洲中心 (Clts))，正在对性行为活跃的人进行毒品和性风险评估， 年轻男性吸毒者。使用民族流行病学方法，将 行为研究和分子流行病学，具有以下研究内容 研究目标：1.患病率：比较肛门生殖道人乳头瘤病毒的患病率 波多黎各HIV+和HIV-年轻男性吸毒者的临床样本感染情况 里科。2.基因变异性：比较HPV亚型在临床上的分布 波多黎各艾滋病毒+和艾滋病毒-年轻男性吸毒者样本。3.性风险 因素：比较艾滋病毒+和艾滋病毒-年轻男性吸毒者，特别注意 可能与以下情况有关的性风险做法(例如性行为、性伙伴关系) HPV亚型和/或HIV/HPV混合感染。

Genital HPV infection is one of the most commonly diagnosed STIs worldwide and its high prevalence may also contribute to increased HIV transmission risk. Although HPV infection has been causally linked with chronic disease sequelae both in men and women, relatively little is known about the distribution of HPV infection and HPV subtypes among in relation to HIV status. Understanding the prevalence, distribution, and general sources of HPV subtypes among both HIV+ and HIV- individuals is important for understanding long term health consequences of HPV. Researchers within the Center for Research on Global Health at the School of Public Health, Medical Sciences Campus, Puerto Rico, in collaboration with the largest publicly funded STI clinic on the island (Centro Latinoamericano de Enfermedades de Transmisi¿n Sexual (CLETS)), are conducting an assessment of drug and sexual risk among sexually active, young male drug users. Using an ethnoepidemiological approach that integrates behavioral research and molecular epidemiology, with the study has the following research objectives: 1. Prevalence: To compare the prevalence of anogenital HPV infection in a clinic-based sample of HIV+ and HIV- young male drug users in Puerto Rico. 2. Genotype Variability: To compare the distribution of HPV subtypes in a clinicbased sample of HIV+ and HIV- young male drug users in Puerto Rico. 3. Sexual Risk Factors: To compare HIV+ and HIV- young male drug users, with particular attention to sexual risk practices (e.g., sexual practices, sex partnering) that may be associated with HPV subtypes and/or HIV/HPV coinfection.