Implementation of School-Entry Policies for Human Papillomavirus Vaccination

7.项目概要/摘要 尽管有预防HPV的疫苗，但接种覆盖率略有增加， 据报道，青少年。在波多黎各（PR）， HPV相关的癌症已被广泛记录，疫苗接种率很低。PR政府 最近颁布了一项政策，要求所有入学的11-12岁青少年接种HPV疫苗， 从下一学年开始（2018-2019）。PR成为美国第五个采用HPV疫苗的州或地区 入学政策。考虑到这一重要的公共政策实施，拟议的研究旨在 检查美国各州HPV疫苗政策传播和实施的地理差异 的执行情况和成果，同时利用及时的机会， 新的学校入学HPV政策在PR深入。本研究将采用多种方法分析调查数据， 免疫登记数据和定性数据，使用定性，相关，比较 案例研究、多水平分析和自然实验设计。此外，与我们当地的 研究结果和建议将反馈给利益攸关方， 决策者告知PR和其他州政策执行的持续演变， 现有政策，并通知正在考虑采用新的HPV疫苗入学的州/地区 政策我们的研究团队处于独特的地位，能够进行这项重要而时间敏感的研究， 我们的长期记录和现有的合作与当地和国家的学术合作伙伴和联盟，重点 关于HPV疫苗如果获得批准，该项目将有助于通知其他国家和地区考虑HPV 免疫政策和今后执行这些政策的研究。 PHS 398/2590（06/09修订版）项目摘要/摘要续页格式

7. Project Summary/Abstract Despite the availability of prophylactic vaccines against HPV, modest increases in vaccination coverage among adolescents has been reported. In Puerto Rico (PR), where disparities in incidence, mortality, and survival of HPV-related cancers have been extensively documented, vaccination rates are low. The PR government recently enacted a policy to require HPV vaccination for all adolescents' ages 11-12 years who enroll in schools, beginning the next academic year (2018-2019). PR became the 5th US state or territory to adopt an HPV vaccine school-entry policy. Taking into account this important public policy implementation, the proposed study aims to examine geographic variation in the dissemination and implementation of HPV vaccine policies across US states and territories, while taking advantage of the timely opportunity to study the implementation and outcomes of the new school-entry HPV policy in PR in depth. This study will use a multi-method approach to analyze survey data, immunization registry data, and qualitative data using a combination of qualitative, correlational, comparative case study, multilevel analysis and natural experiment designs. Additionally, and in collaboration with our local and national partners, the study findings and recommendations will be disseminated back to stakeholders and decision makers to inform the ongoing evolution of the policy implementation in PR and other states with existing policies, and to inform states/territories that are considering adopting a new HPV vaccine school entry policy. Our research team is uniquely positioned to be able to carry this important and time-sensitive study given our long track record and existing collaborations with local and national academic partners and coalitions focusing on HPV vaccination. If granted, this project will serve to inform other states and territories considering HPV immunization policies and future implementation research on these policies. PHS 398/2590 (Rev. 06/09) Project Summary/Abstract Continuation Format Page