Implementation of School-Entry Policies for Human Papillomavirus Vaccination

7.项目摘要/摘要 尽管有针对HPV的预防性疫苗可用，但疫苗接种覆盖率在 据报道，有青少年感染。在波多黎各(PR)，在那里发病率、死亡率和存活率存在差异 HPV相关癌症已经有了广泛的记录，疫苗接种率很低。公关政府 最近颁布了一项政策，要求所有11至12岁的在校青少年接种HPV疫苗， 从下一学年(2018-2019年)开始。PR成为美国第五个采用HPV疫苗的州或地区 入学政策。考虑到这一重要的公共政策执行情况，拟议的研究旨在 检查在美国各州传播和实施HPV疫苗政策的地理差异 和领土，同时利用及时的机会研究《 新入学HPV政策在公关中的深入。这项研究将采用多种方法分析调查数据， 免疫登记数据和定性数据的组合使用定性、相关、比较 案例研究、多水平分析和自然实验设计。此外，并与我们当地的合作 和国家合作伙伴，研究结果和建议将传回给利益攸关方和 决策者将告知PR和其他州的政策执行的持续演变 现有政策，并通知正在考虑采用新的HPV疫苗入学的州/地区 政策。我们的研究团队处于独特的地位，能够进行这项重要的、对时间敏感的研究 我们长期的记录以及与地方和国家学术伙伴和联盟的现有合作，专注于 关于HPV疫苗接种。如果获得批准，这个项目将通知其他考虑HPV的州和地区。 免疫政策和未来对这些政策的执行研究。 PHS 398/2590(版本06/09)项目摘要/摘要续写格式页面

7. Project Summary/Abstract Despite the availability of prophylactic vaccines against HPV, modest increases in vaccination coverage among adolescents has been reported. In Puerto Rico (PR), where disparities in incidence, mortality, and survival of HPV-related cancers have been extensively documented, vaccination rates are low. The PR government recently enacted a policy to require HPV vaccination for all adolescents' ages 11-12 years who enroll in schools, beginning the next academic year (2018-2019). PR became the 5th US state or territory to adopt an HPV vaccine school-entry policy. Taking into account this important public policy implementation, the proposed study aims to examine geographic variation in the dissemination and implementation of HPV vaccine policies across US states and territories, while taking advantage of the timely opportunity to study the implementation and outcomes of the new school-entry HPV policy in PR in depth. This study will use a multi-method approach to analyze survey data, immunization registry data, and qualitative data using a combination of qualitative, correlational, comparative case study, multilevel analysis and natural experiment designs. Additionally, and in collaboration with our local and national partners, the study findings and recommendations will be disseminated back to stakeholders and decision makers to inform the ongoing evolution of the policy implementation in PR and other states with existing policies, and to inform states/territories that are considering adopting a new HPV vaccine school entry policy. Our research team is uniquely positioned to be able to carry this important and time-sensitive study given our long track record and existing collaborations with local and national academic partners and coalitions focusing on HPV vaccination. If granted, this project will serve to inform other states and territories considering HPV immunization policies and future implementation research on these policies. PHS 398/2590 (Rev. 06/09) Project Summary/Abstract Continuation Format Page