Identifying cell type specific biomarkers of recurrent oral squamous cell carcinoma and mapping cancer-stroma interactions using single cell biology and cell-to-cell communication networks

点击翻译按钮获取中文摘要

Cancer is a major cause of death in Australia. Despite advances in our understanding of the mutations that occur and the sets of genes expressed in cancer we have a major gap in our understanding of what is happening within tumours. Using new single cell technology we will generate new molecular portraits of cancers that give us understanding of the sets of genes expressed on individual cancer cells, the normal cells within a tumour and how they interact with cancer cells to form a tumour.