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Evaluation of a social-networking intervention to reduce cancer-related distress

评估社交网络干预措施以减少癌症相关的痛苦

基本信息

批准号：
7876785
负责人：
JASON E OWEN
金额：
$ 7.43万
依托单位：
LOMA LINDA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-07-01 至 2013-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7876785
关键词：
Address Adoption Adult Behavioral Cancer Survivor Caring Communication Control Groups Coping Skills Data Diagnosis Distress Educational Intervention Evaluation Exhibits Exposure to Face Generations Goals Head Health Health Services Accessibility Individual Internet Intervention Learning Life Linguistics Literature Malignant Neoplasms Measures Meta-Analysis Moods Participant Patient Self-Report Patients Procedures Process Psychosocial Assessment and Care Quality of life Randomized Randomized Controlled Trials Registries Relative (related person)Research Services Social Network Structure Survivors System Technology Time Waiting Lists Woman arm base cancer type clinically significant control trial design disturbance in affect effective intervention experience follow-up improved interest malignant breast neoplasm member psychologic psychosocial public health relevance randomized trial satisfaction skills training success trial comparing web site web-based social networking

项目摘要

DESCRIPTION (provided by applicant): Individuals with cancer face an array of psychosocial needs, and it has been estimated that up to 35% of cancer survivors experience clinically-significant levels of distress. Psychosocial interventions may be effective for improving quality of life and reducing levels of mood disturbance in these patients. Unfortunately, barriers to accessing psychosocial intervention are common, and many are unable to access those services. Internet- based psychosocial interventions improve accessibility of care and offer additional methodological advantages, including the ability to easily collect self-report data, track exposure to the intervention, and evaluate effects of specific intervention components. A study conducted by the PI is one of only three randomized trials of the effects of internet-based psychosocial intervention on adjustment to cancer, and all three of these trials were limited to now-outdated Internet interventions provided exclusively to women with breast cancer. There is a clear and pressing need to evaluate an internet-based intervention that: a) has modern features that will increase the amount of time spent interacting with intervention components (i.e., social-networking features), b) is inclusive of other cancers (i.e., not just breast cancer), and c) employs a system for carefully tracking levels of behavioral engagement with the intervention. The specific aims of the proposed study are 1) to evaluate the feasibility of a randomized, controlled trial of an online social-networking intervention and to identify key strengths and weaknesses of the intervention materials and 2) to estimate effect sizes necessary for adequately powering a larger controlled trial comparing face-to-face and online interventions. To accomplish these aims, a registry-based recruitment procedure will be used to identify recently diagnosed individuals with cancer who are currently experiencing significant cancer-related distress. Individuals interested in participating in the study will be randomized to receive access to a 12-week internet-based treatment group or to a 12-week waiting list control group. Subjects assigned to the treatment group will have access to a group discussion board, a structured 12-week coping-skills training course, professional facilitation of the group, a real-time chat board, and personal profiles established by other group members. Subjects will be asked to complete online self-report measures of distress, mood disturbance, and quality of life at baseline and again after participation in the 12-week group. Wait-list control subjects will be able to join a group after they complete the 12-week assessment and will be asked to complete a 24-week assessment in order to measure change over time. It is hypothesized that the treatment group will show greater improvements in quality of life and mood disturbance compared to the control group and that greater levels of engagement with the intervention materials will be associated with greater improvements in mood and quality of life. Long-term goals of the research team are to continually improve effect sizes and accessibility of psychosocial interventions for cancer survivors and to evaluate the effects of internet-based and face-to-face interventions in a head-to-head trial. PUBLIC HEALTH RELEVANCE: Only a handful of studies have evaluated the effects of internet-based psychological treatments for distress in those living with cancer. The proposed study will evaluate whether a website developed specifically for providing psychological treatment and enhancing communication between cancer survivors can improve distress among cancer survivors who indicate that they have high levels of distress. If successful, the study will also provide valuable information needed to improve the treatment and to adequately conduct a larger trial comparing internet-based and face-to-face treatments.

癌症患者面临着一系列的心理社会需求，据估计，高达35%的癌症幸存者经历了临床显著水平的痛苦。心理社会干预可能对改善这些患者的生活质量和降低情绪障碍水平有效。不幸的是，获得心理社会干预的障碍很普遍，许多人无法获得这些服务。基于互联网的心理社会干预改善了护理的可及性，并提供了额外的方法优势，包括能够方便地收集自我报告数据，跟踪干预措施的暴露情况，并评估具体干预措施的效果。PI进行的一项研究是仅有的三项基于互联网的心理社会干预对适应癌症的影响的随机试验之一，所有这三项试验都仅限于专门为乳腺癌妇女提供的现已过时的互联网干预。有一个明确和迫切的需要，以评估一个基于互联网的干预，a）具有现代化的功能，将增加所花费的时间与干预组件（即，社交网络特征），B）包括其他癌症（即，不仅仅是乳腺癌），以及c）采用一种系统，用于仔细跟踪与干预的行为参与水平。拟议研究的具体目的是：1）评估在线社交网络干预的随机对照试验的可行性，并确定干预材料的关键优势和劣势; 2）估计比较面对面和在线干预的更大对照试验所需的有效量。为了实现这些目标，将使用基于登记的招募程序来识别最近诊断出患有癌症的个人，这些人目前正在经历与癌症相关的重大痛苦。有兴趣参加这项研究的个人将被随机分配到12周的基于互联网的治疗组或12周的等待名单对照组。被分配到治疗组的受试者将可以访问小组讨论板、结构化的12周应对技能培训课程、小组的专业促进、实时聊天板以及其他小组成员建立的个人资料。将要求受试者在基线时和参加12周组后再次完成在线自我报告的痛苦、情绪障碍和生活质量测量。等待名单对照受试者在完成12周评估后将能够加入一个组，并将被要求完成24周评估，以测量随时间的变化。据推测，与对照组相比，治疗组的生活质量和情绪障碍将得到更大的改善，并且对干预材料的更高参与水平将与情绪和生活质量的更大改善相关。研究团队的长期目标是不断提高癌症幸存者心理社会干预的效果和可及性，并在一项面对面的试验中评估基于互联网和面对面干预的效果。公共卫生关系：只有少数研究评估了基于互联网的心理治疗对癌症患者痛苦的影响。这项拟议的研究将评估专门为提供心理治疗和加强癌症幸存者之间的沟通而开发的网站是否可以改善那些表示他们有高水平痛苦的癌症幸存者的痛苦。如果成功，该研究还将提供改善治疗所需的有价值的信息，并充分进行更大规模的试验，比较基于互联网和面对面的治疗。