University College London CRUCIBLE, supported by BBSRC, EPSRC, ESRC and MRC

伦敦大学学院 CRUCIBLE，由 BBSRC、EPSRC、ESRC 和 MRC 支持

• 批准号: G0700729/1
• 负责人: Nick Tyler
• 金额: $ 355.83万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2008
• 资助国家: 英国
• 起止时间: 2008 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0700729%2F1
• 关键词: University; College; London; CRUCIBLE; supported

Advances in medical science over the past fifty years have resulted in increasingly ageing populations which now present a major issue for developed and developing countries alike. The challenge for society in the twenty-first century is to ensure that this increased longevity is accompanied by the maintenance of quality of life. The World Health Organisation defines ?active ageing? as ?the process of optimising opportunities for health, participation and security in order to enhance quality of life as people age?. An understanding of the ageing process throughout an individual?s lifetime and what parameters determine quality of life are crucial to conducting research which will provide meaningful solutions on which to base policy decisions. This will need to encompass research on: the basic biology of ageing; diseases/conditions which affect individuals as they age both physically and mentally; therapeutic and other interventions to ameliorate morbidity; epidemiology of ageing populations; engineering, architectural and design considerations; social and cultural issues; ethical and legal ramifications; economic factors. Researchers working in all of these areas can make significant individual contributions to the subject but what is increasingly required is a ?holistic? approach where not only do outcomes in one area inform research in other disciplines but where investigators are able to work together to tackle specific issues (interdisciplinary). Although it is recognised that this method of conducting research is essential to tackling all the major global issues, it is still relatively new and investigators trained to think in this way are few in number. UCL has expertise and experience in all the disciplines listed above and the aim of the Centre will be to add-value to existing research in ageing by encouraging and facilitating a more interdisciplinary approach. Of crucial importance will be the education programmes that are planned which will produce a cadre of future researchers, trained to think more broadly across the disciplines, who are comfortable working outside their core areas of expertise. A further important feature of the Centre will be the involvement of the end-users of the research - the ageing population, whether fit or infirm and frail, - to ensure that the work undertaken and the new ideas generated are truly relevant. A high priority of the Centre will therefore be to ensure translation of outcomes into meaningful benefits for the Lifelong Health and Wellbeing of the general population.

过去五十年来医学科学的进步导致人口日益老龄化，这现在对发达国家和发展中国家都是一个重大问题。21世纪社会面临的挑战是确保在延长寿命的同时保持生活质量。世界卫生组织的定义是？积极老龄化?是吗?优化保健、参与和安全机会的过程，以便随着人们年龄的增长提高生活质量。对整个个体衰老过程的理解？人的一生以及决定生活质量的参数对于开展研究至关重要，这些研究将为政策决策提供有意义的解决方案。这将需要包括以下研究：衰老的基本生物学；随着个人年龄的增长，身体和精神都会受到影响的疾病/状况；减少发病率的治疗和其他干预措施；老龄人口流行病学；工程、建筑和设计方面的考虑；社会和文化问题；道德和法律后果；经济因素。在所有这些领域工作的研究人员都可以对这一主题做出重大的个人贡献，但越来越需要的是一个“整体的”。在这种方法中，不仅一个领域的成果可以为其他学科的研究提供信息，而且研究人员能够共同努力解决具体问题（跨学科）。尽管人们认识到这种进行研究的方法对于解决所有重大的全球问题至关重要，但它仍然相对较新，受过这种思维训练的研究人员数量很少。伦敦大学学院拥有上述所有学科的专业知识和经验，该中心的目标是通过鼓励和促进更多跨学科的方法，为现有的老龄化研究增加价值。至关重要的是，计划中的教育项目将培养一批未来的研究人员骨干，这些研究人员经过培训，能够更广泛地跨学科思考，能够在自己的核心专业领域之外工作。中心的另一个重要特点将是研究的最终用户- -老龄人口，不论健康或体弱多病- -的参与，以确保所进行的工作和产生的新想法是真正相关的。因此，该中心的一个高度优先事项将是确保将成果转化为对一般人口的终身健康和福祉有意义的好处。