An Evaluation of Focal Therapy in the Treatment of Localized Prostate Cancer An Evaluation of Focal Therapy in th

局部治疗局部前列腺癌的局部治疗评价 局部前列腺癌局部治疗的评价

基本信息

  • 批准号:
    G0701302/1
  • 负责人:
  • 金额:
    $ 16.08万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Fellowship
  • 财政年份:
    2008
  • 资助国家:
    英国
  • 起止时间:
    2008 至 无数据
  • 项目状态:
    已结题

项目摘要

The choice for men who have prostate cancer that has not spread outside the gland is between active surveillance and treating the whole gland with surgery or radiotherapy. Active surveillance involves monitoring the disease using blood tests and repeated biopsies every 2-3 years. Treatment is given only if the cancer shows signs of progressing. The benefit of whole-gland treatment in reducing the risk of dying from cancer is 5% or less within 10 years. However, treatment carries risk of incontinence, impotence and rectal problems. These occur because treating the whole gland leads to damage to structures immediately surrounding the prostateThis programme of research will see if prostate cancer management can be developed in a similar way to how breast cancer treatment changed two decades ago. Women usually had to undergo an operation to remove the whole breast whereas currently, most women undergo a lumpectomy of only the cancer. This proposal will evaluate a similar principal in prostate cancer. In other words, in men with prostate cancer can we destroy only the areas of cancer and achieve lower side-effects. At the same time, can we maintain good cancer control.
对于患有尚未扩散到腺体之外的前列腺癌的男性,他们的选择是积极监测和通过手术或放疗治疗整个腺体。主动监测包括每 2-3 年使用血液检测和重复活检来监测疾病。仅当癌症出现进展迹象时才进行治疗。全腺治疗在 10 年内将癌症死亡风险降低 5% 或更少。然而,治疗存在失禁、阳痿和直肠问题的风险。发生这种情况是因为治疗整个腺体会导致前列腺周围的结构受损。该研究计划将看看前列腺癌的治疗是否可以采用与二十年前乳腺癌治疗改变类似的方式进行。女性通常必须接受手术切除整个乳房,而目前,大多数女性仅接受癌症的肿瘤切除术。该提案将评估前列腺癌的类似原理。换句话说,对于患有前列腺癌的男性,我们可以仅破坏癌症区域并实现较低的副作用。同时,我们能否保持良好的癌症控制。

项目成果

期刊论文数量(0)
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会议论文数量(0)
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Hashim Ahmed其他文献

2049 MAGNETIC RESONANCE IMAGE-GUIDED PROSTATE BIOPSY VERSUS TRANSPERINEAL TEMPLATE PROSTATE BIOPSY IN THE DIAGNOSIS OF CLINICALLY SIGNIFICANT PROSTATE CANCER
  • DOI:
    10.1016/j.juro.2012.02.2214
  • 发表时间:
    2012-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Veeru Kasivisvanathan;Robert Dufour;Caroline Moore;Hashim Ahmed;Alex Freeman;Susan Charman;Clare Allen;Jan van der Meulen;Mark Emberton
  • 通讯作者:
    Mark Emberton
MP53-03 TRANSPERINEAL MRI VISUALLY-TARGETED PROSTATE BIOPSIES COMPARED TO TEMPLATE MAPPING BIOPSY IN 534 MEN REQUIRING FURTHER RISK STRATIFICATION
  • DOI:
    10.1016/j.juro.2016.02.500
  • 发表时间:
    2016-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Alistair Grey;Tom Hartingon;Clare Allen;Manit Arya;Mark Emberton;Alex Freeman;Caroline Moore;Shonit Punwani;Navin Ramachandran;Giorgia Trevisan;Miles Walkden;Hashim Ahmed
  • 通讯作者:
    Hashim Ahmed
MP67-19 MORPHOLOGICAL ASSESSMENT OF ANTERIOR LESIONS ON PROSTATE MULTI-PARAMETRIC MAGNETIC RESONANCE IMAGING.
  • DOI:
    10.1016/j.juro.2014.02.2086
  • 发表时间:
    2014-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Ahmed El-Shater Bosaily;Alex Freeman;Mark Emberton;Hashim Ahmed;Alex Kirkham
  • 通讯作者:
    Alex Kirkham
Building Capacity of Teachers and Trainers in Technical and Vocational Education and Training (TVET) in Sudan
苏丹技术和职业教育与培训 (TVET) 教师和培训师的能力建设
  • DOI:
  • 发表时间:
    2010
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Hashim Ahmed
  • 通讯作者:
    Hashim Ahmed
PD43-06 A MULTIVARIATE LOGISTIC REGRESSION INVESTIGATING WHICH FACTORS INFLUENCE DETECTION OF CLINICALLY SIGNIFICANT CANCER BY MRI-TARGETED PROSTATE BIOPSY
  • DOI:
    10.1016/j.juro.2017.02.1911
  • 发表时间:
    2017-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Veeru Kasivisvanathan;Osayuki Nehikhare;Sara Renshaw;Susan Charman;Jan van der Meulen;Shonit Punwani;Alistair Grey;Henrietta Mair;Esmee van der Saar;Ross Warner;Hashim Ahmed;Mark Emberton;Caroline Moore
  • 通讯作者:
    Caroline Moore

Hashim Ahmed的其他文献

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{{ truncateString('Hashim Ahmed', 18)}}的其他基金

Improving the Diagnosis and Treatment of Localised Prostate Cancer
改善局限性前列腺癌的诊断和治疗
  • 批准号:
    G1002509/1
  • 财政年份:
    2011
  • 资助金额:
    $ 16.08万
  • 项目类别:
    Fellowship

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  • 批准号:
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Longitudinal structural and cognitive functional imaging and outcome prediction in focal epilepsy treated with gene therapy and surgical resection.
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粘着斑激酶在治疗耐药性前列腺肿瘤中的作用
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Cortical excitability in refractory focal epilepsy treated with novel gene therapy and conventional resective surgery
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Establishment of focal therapy for localized prostate cancer with cancer localization and tracking technology based on the artificial intelligence
基于人工智能的癌症定位和追踪技术建立局限性前列腺癌的局部治疗
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局灶性癫痫发作电疗法(FEAST)治疗重度抑郁症患者的随机对照试验
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