A randomised controlled trial of Focal Electrically Administered Seizure Therapy (FEAST) in patients with severe depression

局灶性癫痫发作电疗法（FEAST）治疗重度抑郁症患者的随机对照试验

• 批准号: nhmrc : GNT1159769
• 金额: $ 261.65万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-controlled-trial-severe-depression/1379093
• 关键词: randomised; controlled; trial; Focal; Electrically

Severe depression is devastating for those affected and is often accompanied by a significant risk of suicide. Electroconvulsive therapy (ECT) is the most effective acute treatment for severe depression. Though highly effective, the use of ECT is limited by cognitive, particularly memory, side effects. This randomised controlled trial will assess FEAST, a new form of ECT, vs conventional ECT. We expect FEAST will have the high efficacy of ECT, but much less effects on memory and thinking.

严重的抑郁症对那些受影响的人来说是毁灭性的，并且经常伴随着巨大的自杀风险。电休克治疗(ECT)是治疗重度抑郁症最有效的急性治疗方法。尽管ECT非常有效，但它的使用受到认知，特别是记忆副作用的限制。这项随机对照试验将评估FEAST，一种新的ECT形式，与传统ECT相比。我们预计，FEAST将具有ECT的高效率，但对记忆和思维的影响要小得多。