Computer-Based Treatment for Drug Dependence

基于计算机的药物依赖性治疗

• 批准号: 8099561
• 负责人: BRENT A. MOORE
• 金额: $ 18.13万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-15 至 2012-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8099561
• 关键词: Agonist; Area; Behavior Therapy; Buprenorphine; Cognitive Science; Cognitive Therapy; Computer Assisted; Computers; Counseling; Data; Development; Disadvantaged; Drug Addiction; Drug abuse; Effectiveness; Evaluation; Generations; Goals; Health Services Accessibility; Heroin; Individual; Intervention; Knowledge; Maintenance; Manuals; Mental Depression; Mental disorders; Methods; Modality; Modification; Opiate Addiction; Opiates; Opioid; Outcome; Patients; Pharmaceutical Preparations; Phase; Physicians; Physicians' Offices; Pilot Projects; Policies; Principal Investigator; Professional counselor; Provider; Psychotherapy; Qualitative Research; Randomized; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Resistance; Resources; Sampling; Services; Substance abuse problem; Surveys; System; Technology; Telephone; Testing; Therapeutic; Therapeutic Uses; Time; Training; Treatment Efficacy; Treatment outcome; United States; Voice; Wages; alternative treatment; base; career; career development; cost; cost effective; improved; interest; methadone maintenance; novel; opioid abuse; pilot trial; primary care setting; programs; prototype; public health relevance; response; skills; statistics; treatment as usual

DESCRIPTION (provided by applicant): This is a revised application for a K01 to launch an independent research program on the use of Therapeutic Interactive Voice Response (TIVR) and other computer-assisted methods to provide drug counseling to patients receiving office-based buprenorphine maintenance and other drug abuse treatment. This application builds on my expertise in cognitive psychology, computer technologies, drug counseling, drug treatment in primary care settings, and statistics, and takes advantage of the unique resources at Yale. A K01 would provide salary support at a critical juncture in my career, free me up from other projects, and allow me to devote 100% toward becoming an independent investigator. For my training, the K01 would allow me to increase my skills and knowledge in 3 areas: 1) computer based interventions for substance abuse and other psychiatric disorders, 2) the development and evaluation of manual-guided behavioral interventions, and 3) qualitative research methods. For my independent research, I propose to conduct a research project in 3 phases to develop and evaluate a TIVR prototype providing cognitive and behavioral treatment (CBT) to opioid dependent patients receiving buprenorpine maintenance in a primary care setting. The three research phases will involve the generation, testing, and modification of TIVR individual treatment modules. Phase 1 will involve feasibility testing of 10 generated modules across 4 iterations. Phase 2 will compare a single module/session of the TIVR system to an educational video presentation condition and a single therapist-provided session on proximal outcomes of effectiveness among opiate-dependent patients initiating buprenorphine treatment (n = 60). Phase 3 will consist of a pilot trial of TIVR for buprenorphine maintained patients in a primary care setting. Forty patients will be randomly assigned to either TIVR, receiving access to the 10 module prototype for 4 weeks, or to treatment-as-usual. This pilot will provide initial evidence of TIVR efficacy and indicators of the feasibility and acceptability of using TIVR in office-based settings. PUBLIC HEALTH RELEVANCE: Development of an effective, inexpensive, and easily accessible computer based CBT for drug abuse patients in primary care settings would greatly expand and improve available substance abuse services.

描述（由申请人提供）：这是K 01的修订申请，旨在启动一项关于使用治疗性交互式语音应答（TIVR）和其他计算机辅助方法为接受基于办公室的丁丙诺啡维持治疗和其他药物滥用治疗的患者提供药物咨询的独立研究项目。这个应用程序建立在我的专业知识，认知心理学，计算机技术，药物咨询，药物治疗在初级保健设置，和统计，并利用在耶鲁大学的独特资源。K 01将在我职业生涯的关键时刻提供工资支持，将我从其他项目中解放出来，并允许我100%致力于成为一名独立调查员。对于我的培训，K 01将使我在3个领域增加我的技能和知识：1）基于计算机的药物滥用和其他精神疾病干预，2）手动指导行为干预的开发和评估，以及3）定性研究方法。对于我的独立研究，我建议分3个阶段进行研究项目，以开发和评估TIVR原型，为在初级保健环境中接受丁丙诺平维持治疗的阿片类药物依赖患者提供认知和行为治疗（CBT）。这三个研究阶段将涉及TIVR个人治疗模块的生成、测试和修改。第1阶段将涉及在4次迭代中对10个生成的模块进行可行性测试。第2阶段将在开始丁丙诺啡治疗的阿片类药物依赖患者（n = 60）中比较TIVR系统的单个模块/会话与教育视频演示条件和治疗师提供的单个会话的近端有效性结局。III期将包括在初级保健环境中对丁丙诺啡维持患者进行TIVR的试点试验。将40例患者随机分配至TIVR组（接受10个模块原型治疗4周）或常规治疗组。该试点将提供TIVR有效性的初步证据，以及在办公室环境中使用TIVR的可行性和可接受性的指标。 公共卫生相关性：开发一个有效的，廉价的，易于访问的计算机为基础的CBT药物滥用患者在初级保健设置将大大扩大和改善现有的药物滥用服务。

项目成果

Recovery and URICA stage-of-change scores in three marijuana treatment studies.

三项大麻治疗研究中的恢复和 URICA 变化阶段评分。

• DOI: 10.1016/j.jsat.2008.03.004
• 发表时间: 2008
• 期刊: Journal of substance abuse treatment
• 影响因子: 3.9
• 作者: Callaghan,RussellC;Taylor,Lawren;Moore,BrentA;Jungerman,FlaviaS;Vilela,FabianaAndrioniDeBiaze;Budney,AlanJ
• 通讯作者: Budney,AlanJ

The Availability of Ancillary Counseling in the Practices of Physicians Prescribing Buprenorphine.

• DOI: 10.1097/adm.0000000000000247
• 发表时间: 2016-09
• 期刊: Journal of addiction medicine
• 影响因子: 5.5
• 作者: Barry DT;Fazzino T;Necrason E;Ginn J;Fiellin LE;Fiellin DA;Moore BA
• 通讯作者: Moore BA