Southeast Regional Centers of Excellence for Biodefense & Emerging Infectious Di

描述(由申请者提供)：地区IV东南地区新出现感染和生物防御卓越中心(SERCEB)由东南部的6个成员机构和15个附属机构组成。北卡罗来纳大学教堂山分校是牵头机构，成员机构包括杜克大学、埃默里大学、范德比尔特大学、阿拉巴马大学伯明翰分校和佛罗里达大学盖恩斯维尔分校。SERCEB的目标是开发新的疫苗、疗法和诊断方法，以更好地保护国家免受潜在的生物恐怖分子和新出现的传染病威胁。这是通过使用尖端科学和技术进行跨学科和协作研究来实现的。SERCEB通过教育计划、支持创新的新项目以及其世界级研究人员之间的协同互动，为生物防御工作带来了新的研究人员。 相关性：SERCEB的使命是对新出现的传染病和其他生物防御剂进行研究，以便为我国潜在的生物疗法开发疫苗、疗法和诊断方法。 战略管理计划/核心A：战略计划和管理(核心领导人，P.Sparling) 核心A描述(由申请人提供)：核心A是行政核心，负责监督整个SERCEB联合体的所有SERCEB活动。主要目标是通过管理、协调和监督所有SERCEB活动来促进所有SERCEB项目的成功。这包括所有研究计划和核心、职业发展和教育计划及活动、发展项目和试点研究项目、财务监测和监督、合规和监管活动，以及与SERCEB计划相关的所有人员、材料、数据和设施的生物安全和安全问题。 核心A的组成部分位于六个成员机构(北卡罗来纳大学教堂山分校、杜克大学、埃默里大学、阿拉巴马大学伯明翰分校、佛罗里达大学和范德比尔特大学)，所有这些大学都在SERCEB指导委员会中有代表。另一个核心A部分位于密歇根大学，由菲利普·汉纳代表SERCEB指导委员会。核心A的主要行政部门由SERCEB主任P.Frederick Sparling领导，位于北卡罗来纳大学。 应急准备和响应计划通过杜克大学和埃默里大学的核心A进行管理。职业发展计划通过埃默里大学的核心A进行管理。 相关性：行政核心最终负责确保SERCEB的使命得以完成，即对新出现的传染病和其他生物防御剂进行研究，为我国潜在的生物疗法开发疫苗、疗法和诊断。

DESCRIPTION (provided by applicant): The Region IV Southeast Regional Center of Excellence for Emerging Infections and Biodefense (SERCEB) consists of six member institutions and 15 affiliate institutions across the Southeast. The University of North Carolina at Chapel Hill is the lead institution, with member institutions including the Duke University, Emory University, Vanderbilt University, the University of Alabama at Birmingham and the University of Florida-Gainesville. The goals of SERCEB are to develop new vaccines, therapeutics and diagnostics to better protect the nation against potential bioterrorist and emerging infectious disease threats. This is accomplished through interdisciplinary and collaborative research using cutting-edge science and technologies. SERCEB brings new investigators to the biodefense effort through a combination of educational programs, support of innovative new projects, and the synergistic interactions among its world-class investigators. RELEVANCE: The mission of SERCEB is to conduct research on emerging infectious diseases and other biodefense agents for the development of vaccines, therapeutics, and diagnostics for potential biothreats to our nation is fulfilled. STRATEGIC MANAGEMENT PLAN/CORE A: Strategic Plan and Management (Core Leader, P. Sparling) CORE A DESCRIPTION (provided by applicant): Core A, the Administrative Core, oversees all SERCEB activities across the SERCEB consortium. The primary goal is to promote success for all SERCEB programs by managing, coordinating, and supervising all SERCEB activities. This includes all research programs and cores, career development and educational programs and activities, developmental project and pilot research projects, financial monitoring and oversight, compliance and regulatory activities, and biosafety and security issues for all personnel, materials, data and facilities associated with SERCEB programs. Components of Core A are located at the six member institutions (University of North Carolina at Chapel Hill, Duke University, Emory University, the University of Alabama at Birmingham, the University of Florida, and Vanderbilt University), all of which have representatives on the SERCEB Steering Committee. An additional Core A component is located at the University of Michigan, represented on the SERCEB Steering Committee by Philip Hanna. The Primary Administration component of Core A, led by the SERCEB Director, P. Frederick Sparling, is located at the University of North Carolina. The Emergency Preparedness and Response Program is administered through Core A at both Duke University and Emory University. The Career Developmental Program is administered through Core A at Emory University. RELEVANCE: The Administrative Core is ultimately responsible for ensuring that the mission of SERCEB to conduct research on emerging infectious diseases and other biodefense agents for the development of vaccines, therapeutics, and diagnostics for potential biothreats to our nation is fulfilled.