Training in Pediatric Endocrinology and Diabetes Research

描述（由申请人提供）： 该提案寻求对耶鲁儿科内分泌学/糖尿病研究计划培训的持续支持。该申请寻求增加目前的资金水平（每年2至3名博士后奖学金）。该要求是基于我们的培训计划和导师的跟踪记录;该计划的扩展，包括内分泌研究的所有领域;我们的临床，基础和转化研究计划的质量和多样性;我们的一些学员获得博士学位所需的培训时间延长，以及儿科内分泌学和糖尿病研究领域的医生科学家持续严重短缺。耶鲁大学拥有一系列令人印象深刻的资源来支持这一计划，包括DERC，耶鲁儿童健康研究中心，磁共振研究中心，JDRF低磷血症研究中心，耶鲁肌肉骨骼疾病核心中心，X连锁低磷血症中心，人类和转化免疫学的新计划，以及最近，CTSA支持的耶鲁大学临床研究中心已经改变了该机构为临床和转化研究提供的支持。我们的许多培训教师（即，Tamborlane、Carpenter、Riverland、Sherwin、Shulman、赫罗尔德和Rothman）在所有这些资源中都扮演着重要的领导角色。项目主任和培训教师都是备受尊敬和富有成效的调查人员，他们拥有广泛的同行评审赠款支持，为学员的项目提供资金，他们在培训博士后研究员方面有着出色的记录。博士后学员可以选择五个主要的研究培训领域，包括1）T1 DM技术和治疗，2）自身免疫和T1 DM中的3-细胞保存，3）儿童肥胖和T2 DM，4）骨生物学和疾病以及5）发育生物学。我们的教育活动的核心是研究医学计划（IMP），它提供了一个严格的必修和选修课程的课程沿着两个途径，即以病人为导向和以疾病为导向。成功完成课程工作和论文项目将允许学员获得博士学位。这是通过 医学系。IMP课程可供非博士。候选人的核心 我们的少数族裔招募工作是我们与莫尔豪斯医学院儿科系的关系，该系为他们的学生和住院医生提供暑期奖学金。

DESCRIPTION (provided by applicant): This proposal seeks continued support for the Yale Training in Pediatric Endocrinology/Diabetes Research Program. The application seeks an increase in the current level of funding (from 2 to 3 post-doctoral stipends per year).The request is based on the track record of our training program and mentors; extension of the program to include all areas of endocrine research; the quality and diversity of our clinical, basic and translational research programs; the extended period of training that is required for some of our trainees to obtain a PhD degree and the continuing dire shortage of physician-scientists in pediatric endocrinology and diabetes research. Yale has an impressive array of resources that support this program, including the DERC, the Yale Child Health Research Center, the Magnetic Resonance Research Center, the JDRF Center for the Study of Hypoglycemia, the Yale Core Center for Muscular Skeletal Diseases, the Center for X-linked Hypophosphatemia, the new program in Human and Translational Immunology and, most recently, the CTSA-supported Yale Center for Clinical Investigation that has transformed the support provided for clinical and translational research at this institution. Many of our training faculty (i.e., Tamborlane, Carpenter, Rivkees, Sherwin, Shulman, Herold and Rothman) have major leadership roles in all of these resources. The Program Directors and training faculty are highly respected and productive investigators with extensive peer-reviewed grant support to fund trainees' projects and they have an outstanding track record in training post-doctoral fellows. Post-doctoral trainees can choose between five major areas of research training including 1) T1DM technology & therapeutics, 2) autoimmunity & (3-cell preservation in T1DM, 3) childhood obesity & T2DM, 4) bone biology & disease and 5) developmental biology. A centerpiece of our educational activities is the Investigative Medicine Program (IMP) that provides a rigorous curriculum of required and elective courses along two pathways, i.e. patient-oriented and disease-oriented. Successful completion of course work and thesis project will allow trainees to receive a Ph.D. that is awarded through the Department of Medicine. IMP courses are available for non Ph.D. candidates. The centerpiece of our minority recruitment efforts is our relationship with the Department of Pediatrics at Morehouse School of Medicine that offers summer fellowships to their students and residents.