Career Development Programs in Diabetes Research for Pediatric Endocrinologists

描述(申请人提供)：耶鲁大学医学院和耶鲁大学儿科内分泌科正在寻求成为糖尿病事业发展的卓越中心之一，这将允许年轻的儿科内分泌学家作为糖尿病研究的独立研究者建立学术生涯。在这份K12申请中，我们每年申请~2份医生科学家津贴，为期5年。耶鲁大学拥有一系列令人印象深刻的资源来支持这一计划，包括由CTSA支持的耶鲁临床调查中心(YCCI)、DERC、磁共振研究中心、PET中心、Keck生物技术实验室、小鼠代谢表型中心和许多其他研究核心提供的研究服务和研究设施。项目主任、助理项目主任和教师导师都是备受尊敬和富有成效的研究人员，拥有广泛的同行评审拨款支持，以资助学员的项目，他们在管理许多最相关的研究资源和设施方面发挥着关键的行政作用。我们的教职员工有着广泛合作的悠久历史，在年轻内科科学家的职业发展方面有着出色的记录。教职员工包括三名我们的前K12学者，他们已经发展成为杰出的年轻研究人员。我们的内科科学家学者可以在四个主要研究培训领域(T1D治疗、肥胖/T2 DM、T1D免疫生物学和低血糖/神经生物学)和每个领域的5-8名潜在导师之间进行选择。K12咨询委员会将由这些研究领域的每个领导人以及儿科的其他几名高级教员组成。我们教育项目的核心是耶鲁研究医学项目(IMP)。IMP提供的课程是健康科学研究计划硕士学位课程的一部分，我们所有没有高级学位的学者都可以报名参加。我们的第一批两名K12学者有望在2011年获得临床研究的IMP博士学位。

DESCRIPTION (provided by applicant): Yale University School of Medicine and the Yale Pediatric Endocrinology Section are seeking to be one of the centers of excellence in diabetes career development that will allow young pediatric endocrinologists to establish academic careers as independent investigators in diabetes research. In this K12 application, we are requesting ~2 Physician Scientist stipends per year for 5 years. Yale has an impressive array of resources that will support this program, including the research services and research facilities provided by the CTSA-supported Yale Center for Clinical Investigation (YCCI), DERC, Magnetic Resonance Research Center, the PET Center, the Keck Biotechnology Laboratory, Mouse Metabolic Phenotyping Center and a host of other research cores. The Program Director, Assistant Program Director and faculty mentors are highly respected and productive investigators with extensive peer-reviewed grant support to fund trainees' projects and they play key administrative roles in the management of many of the most relevant research resources and facilities. Our faculty members have a long history of extensive collaborations and an outstanding track record in the career development of young physician scientists. The faculty includes three of our former K12 scholars who have developed into outstanding young investigators. Our physician scientist scholars can choose between four major areas of research training (T1D Therapeutics, Obesity/T2 DM, Immunobiology of T1D and Hypoglycemia/ Neurobiology) and 5-8 potential mentors within each area. The K12 Advisory Committee will be comprised of each of the leaders of theses research areas, along with several other senior faculty members in Pediatrics. A centerpiece of our educational program is the Yale Investigative Medicine Program (IMP). IMP offers courses that are part of the Masters Degree in Health Science Research Program curriculum in which all of our scholars who do not have an advanced degree will enroll. Our first two projected K12 scholars are on track to receive IMP PhD's in clinical investigation in 2011.