Training Grant in Renal Function and Disease

肾功能和疾病培训补助金

• 批准号: 7904942
• 负责人: Phillip Darwin Bell
• 金额: $ 12.02万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-17 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7904942
• 关键词: Disease; Grant; Renal function; Training

DESCRIPTION (provided by applicant): This is a competing renewal of an institutional training grant that supports postdoctoral research training in renal diseases at the Medical University of South Carolina. The training addresses particular areas of strength and collaboration in diabetic nephropathy, non-diabetic glomerulopathies, applied signal transduction relating to glomerular growth and function, proteomics of the kidney, and renal cell biology. In the first two cycles of funding, we have emphasized recruitment of clinician scientists and members of underrepresented minority groups. Our diverse pool of trainees has included 5 Caucasians, 4 African Americans, 1 Latina, and 4 Asian Americans. Five trainees were women, and 9 of the 14 were clinicians. We believe that our success in recruiting clinicians and individuals from diverse groups is a primary strength of our program. Our ultimate goal is to position these early career scientists to be competitive for investigator-initiated grant support along the NIH Roadmap T1 or T2 translational axes. Program faculty provide access to training in methodologies aligned with translational research such as biophysics, renal cell biology, proteomics, high-end microscopy, animal models of renal diseases, and clinical trials. Conceptual alignment with the Roadmap is intentional, as we understand the importance of integrating our trainees into future translational efforts. Our program has been enhanced by key recruitment of basic scientists and clinician scientists to this training program. Our designated preceptors (mentors) derive from a group of diverse yet highly compatible investigators in three closely aligned Divisions of Internal Medicine (Nephrology, Rheumatology, and Endocrinology), augmented by inclusion of selected senior faculty from other clinical and basic science departments with whom the core group already collaborates. Affiliated Faculty participate as co-mentors or provide specialized experiences for the trainees. An experienced Program Director and Fellowship Training Committee, as well as Advisory Committees, provide additional levels of direction, advice, accountability and evaluative capacity. A Trainee Ombudsman provides an extra avenue to assist trainees. The support requested will allow us to continue to attract a diverse pool of talented individuals to facilitate our interdisciplinary and programmatic approach. Such individuals will enter the fellowship with the understanding that a long-term commitment to academic medicine or biomedical investigation is a prerequisite for entry and a long-term goal.

描述（由申请人提供）： 这是一项机构培训补助金的竞争续约，该补助金支持南卡罗来纳州医科大学肾脏疾病的博士后研究培训。该训练涉及糖尿病性肾病，非糖尿病性肾小球病，与肾小球生长和功能，肾脏蛋白质组学有关的特定力量和协作领域。在前两个资金周期中，我们强调招募临床医生和代表性不足的少数群体的成员。我们多样化的学员池包括5名高加索人，4名非裔美国人，1名拉丁裔和4名亚裔美国人。五名学员是女性，其中14位是临床医生。我们认为，我们在招募来自不同群体的临床医生和个人方面的成功是我们计划的主要优势。我们的最终目标是将这些早期的职业科学家定位为在NIH路线图T1或T2转化轴上具有竞争力的竞争力。计划教师提供与转化研究相一致的方法学培训的访问权限，例如生物物理学，肾细胞生物学，蛋白质组学，高端显微镜，肾脏疾病动物模型和临床试验。与路线图的概念一致性是故意的，因为我们了解将学员纳入未来的翻译工作的重要性。通过关键招募基础科学家和临床科学家参加该培训计划，我们的计划得到了增强。我们指定的主持人（导师）源自三个密切对准的内科（肾脏学，流变学和内分泌学）的一组多样化但高度兼容的研究人员，通过包括与其他临床和基础科学部门的其他高级教职员工一起增强，与核心小组已经合作。附属的教职员工作为联合会员或为受训者提供专业经验。经验丰富的计划主任和奖学金培训委员会以及咨询委员会提供了更多的指导，建议，问责制和评估能力。实习监察员提供了额外的途径来协助学员。所需的支持将使我们能够继续吸引各种各样的才华横溢的人，以促进我们的跨学科和程序化方法。这样的人将进入团契，并了解到对学术医学或生物医学调查的长期承诺是进入和长期目标的先决条件。