WCMC Child Neurology Postdoctoral Training on Developmental Neurosciences

描述(由申请者提供)：威尔·康奈尔医学院(WCMC)儿童神经病学部门建议设立神经科学学术发展奖(NSADA)，旨在促进和培育致力于独立研究事业的初级教师儿童神经病学家的职业发展，并使科学培训成为下一代临床神经科学家。由威尔·康奈尔医学院、洛克菲勒大学和纪念斯隆-凯特琳癌症中心的斯隆-凯特琳研究所组成的三机构研究计划为NSADA计划提供了独特的环境。这三个机构认识到国家需要培训生物医学研究人员：(A)对生物医学神经科学有深入的了解，掌握现代研究技能，这将使他们能够进行基础研究，以阐明与人类发育神经疾病有关的基本神经生物学过程；(B)在人类神经生物学、病理生理学和临床神经学，包括儿童神经学方面有很好的基础。我们的计划将指导NSADA学者通过严格的研究生学习课程，提供个人研究重点的灵活性，并在三所大学校园内的领先发展神经科学实验室自由接触经验丰富的导师。学院的多机构组成确保了在所有主要研究学科都有广泛的专业知识，包括最广泛意义上的发展神经科学：神经化学和神经生物学；神经解剖学和基于磁共振的脑成像、细胞和发育神经生物学；神经药理学；计算神经生物学和生物信息学；神经遗传学和基因组学；神经免疫学；分子神经科学；疾病的病理学和机制；以及神经生理学和生物物理学。虽然发展神经学和医学以及婴儿和儿童大脑科学在健康和疾病方面的框架是巨大的，但我们的计划将强调让每个受训人员掌握发展神经生物学技能的主题，使他们能够掌握和应用基础和临床神经科学的现有方法，以提高他们诊断和治疗发育性大脑疾病的能力。 公共卫生相关性：我们的培训计划将使临床医生研究人员具备必要的技能，将基础研究的进步转化为对儿科神经疾病的理解、预防和治疗，并改善公共健康。

DESCRIPTION (provided by applicant): The Weill Cornell Medical College (WCMC) Division of Child eurology proposal for a Neurological Sciences Academic Development Award (NSADA) is designed to facilitate and nurture career development for junior faculty Child Neurologists committed to independent research careers and to enable scientific training ofthe next generation of clinical neuroscientists. The Tri-lnstitutional Research Program comprising Weill Cornell Medical College, The Rockefeller University, and the Sloan-Kettering Institute ofthe Memorial Sloan-Kettering Cancer Center provides a unique environment for an NSADA Program. These three institutions recognize the national need for training biomedical investigators who: (A) have advanced understanding of biomedical neuroscience and a mastery of contemporary research skills, which will allow them to undertake fundamental studies to elucidate basic neurobiological processes pertaining to human developmental neurologic disease; and (B) are well grounded in human neurobiology, pathophysiology and clinical neurology, including child neurology. Our program will guide NSADA Scholars through a rigorous course of postgraduate study that offers flexibility regarding the individual focus of research, and unfettered access to experienced mentors in leading developmental neuroscience laboratories within the Tri-lnstitutional campus. The multi-Institutional makeup of the faculty ensures that there is broad expertise in all ofthe major research disciplines comprising developmental neuroscience in its broadest sense: neurochemistry and neurobiology; neuroanatomy and MR- based brain imaging, cell and developmental neurobiology; neuropharmacology; computational neurobiology and bioinformatics; neurogenetics and genomics; neuro-immunology; molecular neuroscience; pathology and mechanisms of disease; and neurophysiology and biophysics. While the framework of developmental neurology and medicine and the sciences ofthe infant's and child's brain in health and disease is vast, our program will emphasize the theme of having each trainee master skills in developmental neurobiology, which enable them to acquire and apply current methods in basic and clinical neurosciences to improve thir ability to diagnose and treat developmental brain disorders. PUBLIC HEALTH RELEVANCE: Our training program will allow the development of clinician researchers with the skills necessary to transfer advances in basic research to the understanding, prevention, and treatment of pediatric neurologic disorders and improve the public health.