WCMC Child Neurology Postdoctoral Training on Developmental Neurosciences

WCMC 儿童神经学发育神经科学博士后培训

• 批准号: 8299559
• 负责人: BARRY E KOSOFSKY
• 金额: $ 44.97万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8299559
• 关键词: Award; Base of the Brain; Basic Science; Bioinformatics; Biophysics; Brain; Brain Diseases; Brain imaging; Cells; Child; Childhood; Clinical; Commit; Development; Diagnosis; Discipline; Disease; Ensure; Environment; Faculty; Functional disorder; Genomics; Health; Human; Immunology; Individual; Infant; Institutes; Institution; Laboratories; Medicine; Memorial Sloan-Kettering Cancer Center; Mentors; Methods; Molecular; Neuroanatomy; Neurobiology; Neurologic; Neurologist; Neurology; Neuropharmacology; Neurosciences; Pathology; Pediatric Neurology; Prevention; Process; Public Health; Research; Research Personnel; Science; Training; Training Programs; Universities; career; career development; design; developmental neurobiology; experience; flexibility; improved; medical schools; nervous system disorder; neurochemistry; neurogenetics; neurophysiology; next generation; post-doctoral training; programs; public health relevance; skills

DESCRIPTION (provided by applicant): The Weill Cornell Medical College (WCMC) Division of Child eurology proposal for a Neurological Sciences Academic Development Award (NSADA) is designed to facilitate and nurture career development for junior faculty Child Neurologists committed to independent research careers and to enable scientific training ofthe next generation of clinical neuroscientists. The Tri-lnstitutional Research Program comprising Weill Cornell Medical College, The Rockefeller University, and the Sloan-Kettering Institute ofthe Memorial Sloan-Kettering Cancer Center provides a unique environment for an NSADA Program. These three institutions recognize the national need for training biomedical investigators who: (A) have advanced understanding of biomedical neuroscience and a mastery of contemporary research skills, which will allow them to undertake fundamental studies to elucidate basic neurobiological processes pertaining to human developmental neurologic disease; and (B) are well grounded in human neurobiology, pathophysiology and clinical neurology, including child neurology. Our program will guide NSADA Scholars through a rigorous course of postgraduate study that offers flexibility regarding the individual focus of research, and unfettered access to experienced mentors in leading developmental neuroscience laboratories within the Tri-lnstitutional campus. The multi-Institutional makeup of the faculty ensures that there is broad expertise in all ofthe major research disciplines comprising developmental neuroscience in its broadest sense: neurochemistry and neurobiology; neuroanatomy and MR- based brain imaging, cell and developmental neurobiology; neuropharmacology; computational neurobiology and bioinformatics; neurogenetics and genomics; neuro-immunology; molecular neuroscience; pathology and mechanisms of disease; and neurophysiology and biophysics. While the framework of developmental neurology and medicine and the sciences ofthe infant's and child's brain in health and disease is vast, our program will emphasize the theme of having each trainee master skills in developmental neurobiology, which enable them to acquire and apply current methods in basic and clinical neurosciences to improve thir ability to diagnose and treat developmental brain disorders. PUBLIC HEALTH RELEVANCE: Our training program will allow the development of clinician researchers with the skills necessary to transfer advances in basic research to the understanding, prevention, and treatment of pediatric neurologic disorders and improve the public health.

描述（由申请人提供）：威尔康奈尔医学院（WCMC）儿童神经病学分部提出的神经科学学术发展奖（NSADA）旨在促进和培养致力于独立研究事业的初级教师儿童神经学家的职业发展，并使下一代临床神经科学家的科学培训。由威尔康奈尔医学院、洛克菲勒大学和纪念斯隆-凯特琳癌症中心的斯隆-凯特琳研究所组成的三机构研究方案为NSADA方案提供了独特的环境。这三个机构认识到国家需要培训生物医学研究人员，他们：（A）对生物医学神经科学有深入的了解，掌握当代研究技能，这将使他们能够进行基础研究，阐明与人类发育神经疾病有关的基本神经生物学过程;（B）在人类神经生物学、病理生理学和临床神经学，包括儿童神经学方面有良好的基础。我们的计划将指导NSADA学者通过严格的研究生学习课程，提供关于个人研究重点的灵活性，并在三机构校园内领先的发展神经科学实验室中不受限制地获得经验丰富的导师。教师的多机构组成，确保有广泛的专业知识，在所有的主要研究学科，包括发展神经科学在其最广泛的意义上：神经化学和神经生物学;神经解剖学和基于MR的脑成像，细胞和发育神经生物学;神经药理学;计算神经生物学和生物信息学;神经遗传学和基因组学;神经免疫学;分子神经科学;病理学和疾病机制;神经生理学和生物物理学。虽然发育神经学和医学以及婴儿和儿童大脑健康和疾病科学的框架是巨大的，但我们的计划将强调让每个受训者掌握发育神经生物学技能的主题，使他们能够获得和应用基础和临床神经科学的现有方法，以提高诊断和治疗发育性大脑疾病的能力。 公共卫生相关性：我们的培训计划将使临床研究人员能够培养出具有必要技能的临床研究人员，将基础研究的进展转移到儿科神经系统疾病的理解、预防和治疗中，并改善公共健康。