Identifying novel genome instability signatures in cancer

识别癌症中新的基因组不稳定性特征

• 批准号: nhmrc : GNT1091589
• 负责人: Dr Mark Adams
• 金额: $ 30.94万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-novel-genome-signatures-cancer/1345845
• 关键词: Identifying; novel; genome; instability; signatures

Cancer is the single biggest clinical problem facing the world. An underlying hallmark of cancer is the accumulation of errors in the genetic information of a cell which arises through genomic instability. This research project aims to investigate novel molecules identified by our screening that function in response to genomic instability in cancer. This study is expected to define roles for each molecule in the maintenance of genomic stability and predict for patient diagnosis and outcome.

癌症是世界面临的最大的临床问题。癌症的一个潜在特征是由于基因组不稳定性而导致细胞遗传信息中错误的积累。该研究项目旨在研究通过我们的筛选鉴定出的新分子，这些分子可响应癌症中的基因组不稳定性。这项研究预计将定义每个分子在维持基因组稳定性中的作用并预测患者的诊断和结果。