Patient-Oriented Research to Improve Geriatric Care - K24

描述（由申请人提供）：这是一个修订后的竞争更新建议的中期职业生涯研究者奖在以患者为导向的研究（K24）克里斯托弗M。医学博士卡拉汉。该提案要求额外五年的支持（06 - 10年）。前五年的资助是成功的，候选人达到或超过了该奖项的每一个目标。卡拉汉博士是一位内科医生兼科学家，他的研究重点是改善老年人的临床护理。他的具体研究兴趣是痴呆症和晚年抑郁症，并提高初级保健机构中老年人对这些疾病的护理质量。卡拉汉博士是印第安纳州大学医学院的医学教授，也是印第安纳州大学老龄化研究中心的创始主任。该奖项的目的是让候选人建立自己的能力，在老龄化相关的病人为导向的研究，并支持他作为一个导师的初级教师的角色，并发展他作为导师的角色越来越多的“下一代”导师。候选人建议扩展老龄化研究中心的研究实验室，以针对更大的护理连续体，包括护理设施设置。K24的06 - 10年的具体目标是：1。培养下一代的医生科学家和行为科学家在以病人为导向的研究，以改善整个护理连续提供给老年人的护理; 2。利用现有的临床实践和临床试验数据，将这些数据与描述护理设施护理利用率的纵向国家级数据相结合; 3.重新激励候选人对R01型资金的追求，以支持将干预目标扩展到初级保健之外的临床试验。大多数老年人在初级保健环境中得到照顾，候选人仍然致力于改善这种环境中的护理。然而，改善老年人护理的战略必须越来越多地考虑到其他护理场所，例如护理设施和患者家中提供的护理场所。 公共卫生相关性：该项目有两个目标。第一个目标是通过增加接受过老年人临床研究培训的医生-科学家人数，提高国家开展面向患者的研究的能力。第二个目标是通过研究临床干预措施来扩大候选人的研究范围，这些干预措施涉及向老年人提供护理的多个医疗保健提供者和护理场所，包括护理设施。

DESCRIPTION (provided by applicant): This is a revised competing renewal proposal for a Midcareer Investigator Award in Patient- Oriented Research (K24) for Christopher M. Callahan, MD. This proposal requests an additional five years of support (Years 06-10). The first five years of funding were successful and the candidate met or exceeded each of the targeted goals for that award. Dr. Callahan is a physician-scientist whose research focuses on improving the clinical care of older adults. His specific research interests are in dementia and late life depression and improving quality of care for these conditions among older adults in primary care settings. Dr. Callahan is a Professor of Medicine at the Indiana University School of Medicine and the founding Director of the Indiana University Center for Aging Research. The purpose of this Award is to allow the candidate to build his capabilities in aging-related patient-oriented research and to support his role as a mentor for junior faculty and to develop his role as mentor for a growing number of "next generation" mentors. The candidate is proposing to extend the research laboratory at the Center of Aging Research to target a larger segment of the continuum of care, including the nursing facility setting. The specific aims for years 06-10 of the K24 are to: 1. Train the next generation of physician-scientists and behavioral scientists in patient-oriented research to improve the care provided to older adults across the continuum of care; 2. Exploit existing clinical practice and clinical trial data by combining these data with longitudinal state-level data describing utilization of nursing facility care; and 3. Re-invigorate the candidate's pursuit of R01-type funding in support of clinical trials that expand the targets of the intervention beyond the walls of primary care. Most older adults are cared for in primary care settings and the candidate remains committed to improving care in this setting. However, strategies to improve care for older adults must increasingly take into account other sites of care, such as that provided in nursing facilities and in the patient's home. PUBLIC HEALTH RELEVANCE: The project has two goals. The first goal is to increase the nation's capacity to conduct patient-oriented research by increasing the number of physician-scientists trained in clinical research relevant to older adults. The second goal is to expand the Candidate's scope of research by studying clinical interventions that account for the multiple health care providers and sites of care involved in delivering care to older adults, including nursing facilities.