Patient-Oriented Research to Improve Geriatric Care - K24

描述（由申请人提供）：这是一份针对Christopher M. Callahan医学博士的患者导向研究（K24）职业中期研究者奖的修订竞争性续期申请。该申请要求额外的五年支持（06-10年）。前五年的资助是成功的，候选人达到或超过了该奖项的每一个目标。卡拉汉博士是一名医生兼科学家，他的研究重点是改善老年人的临床护理。他的具体研究兴趣是痴呆症和晚年抑郁症，以及在初级保健机构中提高老年人对这些疾病的护理质量。卡拉汉博士是印第安纳大学医学院的医学教授，也是印第安纳大学老龄化研究中心的创始主任。该奖项的目的是让候选人能够在与老年相关的以患者为导向的研究中建立自己的能力，并支持他作为初级教师的导师的角色，并发展他作为越来越多的“下一代”导师的角色。候选人提议将老龄化研究中心的研究实验室扩展到更大范围的连续护理，包括护理设施设置。K24在06-10年的具体目标是：1。在以患者为导向的研究中培训下一代医生科学家和行为科学家，以改善在整个护理过程中为老年人提供的护理；2. 利用现有的临床实践和临床试验数据，将这些数据与描述护理机构护理利用的纵向国家级数据相结合；和3。重新激活候选人对r01型资金的追求，以支持将干预目标扩展到初级保健之外的临床试验。大多数老年人在初级保健机构得到照顾，候选人仍然致力于改善这种情况下的护理。然而，改善老年人护理的战略必须越来越多地考虑到其他护理场所，例如在护理设施和患者家中提供的护理场所。

DESCRIPTION (provided by applicant): This is a revised competing renewal proposal for a Midcareer Investigator Award in Patient- Oriented Research (K24) for Christopher M. Callahan, MD. This proposal requests an additional five years of support (Years 06-10). The first five years of funding were successful and the candidate met or exceeded each of the targeted goals for that award. Dr. Callahan is a physician-scientist whose research focuses on improving the clinical care of older adults. His specific research interests are in dementia and late life depression and improving quality of care for these conditions among older adults in primary care settings. Dr. Callahan is a Professor of Medicine at the Indiana University School of Medicine and the founding Director of the Indiana University Center for Aging Research. The purpose of this Award is to allow the candidate to build his capabilities in aging-related patient-oriented research and to support his role as a mentor for junior faculty and to develop his role as mentor for a growing number of "next generation" mentors. The candidate is proposing to extend the research laboratory at the Center of Aging Research to target a larger segment of the continuum of care, including the nursing facility setting. The specific aims for years 06-10 of the K24 are to: 1. Train the next generation of physician-scientists and behavioral scientists in patient-oriented research to improve the care provided to older adults across the continuum of care; 2. Exploit existing clinical practice and clinical trial data by combining these data with longitudinal state-level data describing utilization of nursing facility care; and 3. Re-invigorate the candidate's pursuit of R01-type funding in support of clinical trials that expand the targets of the intervention beyond the walls of primary care. Most older adults are cared for in primary care settings and the candidate remains committed to improving care in this setting. However, strategies to improve care for older adults must increasingly take into account other sites of care, such as that provided in nursing facilities and in the patient's home. PUBLIC HEALTH RELEVANCE: The project has two goals. The first goal is to increase the nation's capacity to conduct patient-oriented research by increasing the number of physician-scientists trained in clinical research relevant to older adults. The second goal is to expand the Candidate's scope of research by studying clinical interventions that account for the multiple health care providers and sites of care involved in delivering care to older adults, including nursing facilities.