Training Core

项目摘要 国家老龄化研究所（NIA）的首要目标阿尔茨海默病和阿尔茨海默病 和相关痴呆症（AD/ADRD）合作实验室将作为国家资源， 实用临床试验（ePCT），改善痴呆症患者（PWD）及其护理人员的护理 (CGs)，与为他们服务的医疗保健系统（HCS）合作。这一目标的内在要求是， 培训和支持一支有才干的调查人员队伍，准备在今后继续开展这项工作。因此，在本发明中， 国家情报局反倾销/反倾销与反歧视合作实验室的培训核心旨在支持初级调查人员的培训， 成为这个领域的专家。它将通过利用整个NIH AD/ADRD的广泛专业知识来实现这一目标 合作实验室以及美国国立卫生研究院HCS合作实验室的基础工作。在 与其他七个核心合作，培训核心将促进同行，跨专业， 跨学科和跨部门（哥伦比亚-人道主义事务部-政府）的指导和支持，以提高所有人的技能 参与者培训核心将由Christopher M.卡拉汉，医学博士和Alexia M. Torke，MD，两者 他们中的许多人在将初级研究人员培养为独立研究人员方面拥有数十年的经验。的 培训核心的具体目标是：目标1。开发，资助和协调两年的初级职业生涯 发展奖（CDA）计划的MD和博士早期职业培训生谁寻求建立自己的职业生涯 利用AD/ADRD合作实验室的丰富资源，在残疾人中开展ePCT。三个CDA将在 在第3年和第4年各资助一次，共资助6个社区发展援助项目;目标2.制定和实施结构化培训 针对初级研究者在PWD中进行ePCT的所有方面的活动，包括内部 学员（综合发展援助受助人、初级先导计划受助人、工作核心小组的博士后学生），以及 AD/ADRD合作实验室外部的受训人员，包括：1.在波士顿的培训讲习班和务虚会， 3 - 5年和2年。一系列基于网络的视频培训模块。目标3：将CDA接收者和其他 AD/ADRD合作实验室的初级研究人员参与工作组核心的学术活动， 团队（例如，撰写稿件、指导材料），以促进其专业特长和个人 生产力影响：建设国家在AD/ADRD中进行有效ePCT的能力不仅需要 支持试点项目和NIA资助的ePCT，同时培养一支有才华的调查人员队伍， 在未来继续这项工作。因此，在准备一支熟练进行调查的调查人员队伍时， 这一独特的培训核心对AD/ADRD合作实验室的集体努力至关重要 改变来自各种背景的美国人的护理服务的交付，质量和结果， AD/ADRD及其护理人员。

PROJECT SUMMARY The over-riding objective of the National Institute of Aging (NIA) Alzheimer's disease and Alzheimer’s disease and related dementias (AD/ADRD) Collaboratory is to serve as a national resource for the conduct of embedded pragmatic clinical trials (ePCTs) that improve the care of persons with dementia (PWD) and their caregivers (CGs), in partnership with the healthcare systems (HCS) that serve them. Inherent in this objective is the need to train and support a cadre of talented investigators prepared to carry on this work well into the future. As such, the Training Core of the NIA AD/ADRD Collaboratory seeks to support the training of junior investigators to become experts in this field. It will do so by exploiting the expansive expertise across the entire NIH AD/ADRD Collaboratory as well as the foundational work of the National Institutes of Health HCS Collaboratory. In collaboration with the other seven Cores, the Training Core will facilitate peer-to-peer, inter-professional, interdisciplinary, and inter-sector (academia-HCS-government) mentoring and support to raise the skill set of all participants. The Training Core will be co-led by Christopher M. Callahan, MD and Alexia M. Torke, MD, both of whom bring decades of experience in developing junior investigators as independent researchers. The Training Core’s Specific Aims are: Aim 1. To develop, fund, and coordinate a two-year junior career development award (CDA) program for MD and PhD early career trainees who seek to build their career conducting ePCTs in PWD by leveraging the rich resources of the AD/ADRD Collaboratory. Three CDAs will be funded in each of Years 3 and 4, for a total of six CDAs; Aim 2. To develop and implement structured training activities that address all aspects of conducting ePCTs in PWD for junior investigators, including both internal trainees (CDA recipients, junior pilot project awardees, post-doctoral students in Working Core Groups) and trainees external to the AD/ADRD Collaboratory, including: 1. a Training Workshop and Retreat in Boston in Years 3-5, and 2. a series of web-based video training modules. Aim 3. To integrate CDA recipients and other junior investigators within the AD/ADRD Collaboratory into the academic activities of Working Group Cores and Teams (e.g., writing manuscripts, guidance materials) to promote their professional expertise and individual productivity. IMPACT: Building the nation’s capacity to conduct impactful ePCTs in AD/ADRD requires not only supporting pilot projects and NIA-funded ePCTs, but also developing a cadre of talented investigators prepared to carry on this work well into the future. Thus, in preparing a workforce of investigators skilled in conducting ePCTs among PWD, this unique Training Core is essential to the collective effort of an AD/ADRD Collaboratory to transform the delivery, quality, and outcomes of care for Americans from all backgrounds suffering with AD/ADRD and their caregivers.