Training Core

项目总结 国家老龄研究所(NIA)阿尔茨海默病和阿尔茨海默病的首要目标 和相关痴呆症(AD/ADRD)合作实验室将作为开展嵌入式治疗的国家资源 改善痴呆症患者(PWD)及其照顾者护理的实用临床试验(EPCT) (CGS)，与为他们服务的医疗系统(HCS)合作。这一目标所固有的是需要 培训和支持一支有才干的调查人员队伍，准备在今后很好地开展这项工作。因此， NIA AD/ADRD合作实验室的培训核心旨在支持初级调查人员的培训，以 成为这个领域的专家。它将通过利用整个NIH AD/ADRD的广泛专业知识来实现这一点 合作以及国家卫生研究院HCS合作实验室的基础性工作。在……里面 通过与其他七个核心的协作，培训核心将促进点对点、跨专业、 跨学科和跨部门(学术界-HCS-政府)的指导和支持，以提高所有人的技能 参与者。培训核心将由克里斯托弗·M·卡拉汉医学博士和亚历克西亚·M·托克医学博士共同领导 他们带来了数十年将初级调查人员培养为独立研究人员的经验。这个 培训核心的具体目标是：目标1.发展、资助和协调两年的初级职业生涯 为寻求职业发展的医学博士和博士早期职业实习生提供发展奖(CDA)计划 利用AD/ADRD合作实验室的丰富资源，在PWD开展ePCT。三个CDA将是 在第3年和第4年每年提供资金，用于总共6个CDA；目标2.制定和实施有系统的培训 针对初级调查人员在PWD中开展ePCT的所有方面的活动，包括内部 受训人员(CDA获得者、初级试点项目获奖者、工作核心小组的博士后)和 AD/ADRD合作实验室以外的受训人员，包括：1.#年在波士顿举办的培训讲习班和务虚会 3-5年，以及2.一系列基于网络的视频培训模块。目标3.整合CDA接受者和其他 AD/ADRD合作实验室内的初级调查员参与工作组核心和 团队(例如，撰写手稿、指导材料)，以促进他们的专业知识和个人 生产力。影响：建设国家在AD/ADRD开展有影响力的ePCT的能力不仅需要 支持试点项目和NIA资助的ePCT，但也要培养一支有才华的调查人员队伍 把这项工作很好地进行到未来。因此，在培养一支熟练的调查人员队伍时 在残疾人中，这一独特的培训核心对AD/ADRD合作实验室的集体努力至关重要 改变对来自各种背景的美国人的关怀的交付、质量和结果 AD/ADRD和他们的照顾者。

PROJECT SUMMARY The over-riding objective of the National Institute of Aging (NIA) Alzheimer's disease and Alzheimer’s disease and related dementias (AD/ADRD) Collaboratory is to serve as a national resource for the conduct of embedded pragmatic clinical trials (ePCTs) that improve the care of persons with dementia (PWD) and their caregivers (CGs), in partnership with the healthcare systems (HCS) that serve them. Inherent in this objective is the need to train and support a cadre of talented investigators prepared to carry on this work well into the future. As such, the Training Core of the NIA AD/ADRD Collaboratory seeks to support the training of junior investigators to become experts in this field. It will do so by exploiting the expansive expertise across the entire NIH AD/ADRD Collaboratory as well as the foundational work of the National Institutes of Health HCS Collaboratory. In collaboration with the other seven Cores, the Training Core will facilitate peer-to-peer, inter-professional, interdisciplinary, and inter-sector (academia-HCS-government) mentoring and support to raise the skill set of all participants. The Training Core will be co-led by Christopher M. Callahan, MD and Alexia M. Torke, MD, both of whom bring decades of experience in developing junior investigators as independent researchers. The Training Core’s Specific Aims are: Aim 1. To develop, fund, and coordinate a two-year junior career development award (CDA) program for MD and PhD early career trainees who seek to build their career conducting ePCTs in PWD by leveraging the rich resources of the AD/ADRD Collaboratory. Three CDAs will be funded in each of Years 3 and 4, for a total of six CDAs; Aim 2. To develop and implement structured training activities that address all aspects of conducting ePCTs in PWD for junior investigators, including both internal trainees (CDA recipients, junior pilot project awardees, post-doctoral students in Working Core Groups) and trainees external to the AD/ADRD Collaboratory, including: 1. a Training Workshop and Retreat in Boston in Years 3-5, and 2. a series of web-based video training modules. Aim 3. To integrate CDA recipients and other junior investigators within the AD/ADRD Collaboratory into the academic activities of Working Group Cores and Teams (e.g., writing manuscripts, guidance materials) to promote their professional expertise and individual productivity. IMPACT: Building the nation’s capacity to conduct impactful ePCTs in AD/ADRD requires not only supporting pilot projects and NIA-funded ePCTs, but also developing a cadre of talented investigators prepared to carry on this work well into the future. Thus, in preparing a workforce of investigators skilled in conducting ePCTs among PWD, this unique Training Core is essential to the collective effort of an AD/ADRD Collaboratory to transform the delivery, quality, and outcomes of care for Americans from all backgrounds suffering with AD/ADRD and their caregivers.