New Faculty for Craniofacial Tissue Engineering and Biology

说明（由申请人提供）：本拨款申请是针对 RFA-OD-09-005 的响应，题为“通过生物医学研究核心中心支持新教师招聘以增强研究资源”，旨在请求支持在匹兹堡大学牙科医学院 (SDM) 新创建的颅面再生中心 (CCR) 中招聘两名颅面再生领域的额外教员。SDM 领导层和中心主任我们制定了愿景并概述了建立我们的研究能力的清晰路径，旨在创建颅面再生卓越中心。该战略的制定是为了利用匹兹堡大学现有的组织工程优势，该大学在颅面再生领域缺乏协调一致的努力。在其短暂的历史中，CCR 通过吸引工程学院和医学院的教师加入并招募新教师，一直在稳步发展。该核在矿化组织和 TMJ 再生方面发展了 CCR 的当前强度。我们最初的计划是在 SDM 中再招募两名具有专业知识的教员，以补充 CCR 活动并支持其整体使命。然而，由于当前的金融危机，这一努力因预算限制而被搁置。为了继续巩固我们在矿化组织和TM]再生方面的初始实力，并实现成为再生医学卓越中心的目标，我们必须继续招募工作，以建立足够数量对颅面再生感兴趣的教师队伍，并实现这项研究工作的长期可持续性。这笔赠款的资金将为重新参与我们最初计划在金融危机前招聘的两名教员的招聘活动提供机会。这些教师在培养一批关键的研究人员方面发挥了重要作用，他们共同致力于开发颅面再生疗法，更具体地说是矿化组织和颞下颌关节再生。与工程学院和医学院的综合努力将最终提高 CCR 和 SDM 的排名和地位。该奖项将使我们能够朝着建立高质量研究项目的目标迈进，这将带来颅面再生和改善患者护理的革命性方法。 公共卫生相关性：我们建议招聘两名颅面发育生物学和智能生物材料领域的教员，以补充匹兹堡大学颅面再生中心 (CCR) 现有的多学科工作。这将使我们能够实现成为卓越中心的目标，为颅面再生提供革命性的方法，从而改善人类健康。

DESCRIPTION (provided by applicant): This grant application in response to the RFA-OD-09-005 entitled: "Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers" is aimed to request support for the recruitment of two additional faculty members in the area of craniofacial regeneration in the newly created Center for Craniofacial Regeneration (CCR) at the University of Pittsburgh School of Dental Medicine (SDM).SDM leadership and center directors have set a vision and outlined a clear path to build our research capabilities with the aim to create a Center of Excellence in craniofacial regeneration. The strategy was developed to build on the existing tissue engineering strengths at the University of Pittsburgh which was lacking a concerted effort in the field of craniofacial regeneration. During its short history, CCR has been growing at a steady pace by attracting faculty from the Schools of Engineering and Medicine to join in the efforts, and by recruiting new faculty. This nucleus developed the current strength in CCR in mineralized tissue and TMJ regeneration. Our original plan was to recruit two more faculty at the SDM with the expertise that compliment the CCR activities and support its overall mission. However, due to the current financial crisis, this effort was placed on hold due to budgetary constraints. In order to continue to build on our initial strength in the mineralized tissue and TM] regeneration, and achieve our goal to become a Center of Excellence for Regenerative Medicine, we must continue the recruitment effort to build a critical mass of faculty interested in craniofacial regeneration and achieve a long term sustainability of this research effort. The funding from this grant will provide such an opportunity to reengage in recruitment activities of two faculty members that we initially planned to recruit prior to the financial crisis. These faculty are instrumental in creating a critical mass of researchers working together on developing craniofacial regenerative therapies and more specifically mineralized tissue and TMJ regeneration. This integrated effort with the Engineering and Medical Schools will culminate in improved ranking and stature of CCR and SDM. This award will allow us to progress toward our goal to establish high quality research programs which will lead to revolutionary approaches to craniofacial regeneration and improved patient care. PUBLIC HEALTH RELEVANCE: We propose to recruit two faculty in the areas of craniofacial developmental biology and smart biomaterials that complement the existing multidisciplinary efforts at the Center for Craniofacial Regeneration (CCR) at the University of Pittsburgh. This will allow us to achieve our goal of becoming a center of excellence that will provide revolutionary approaches to craniofacial regeneration which will lead to Improving human health.