SENSITIVITY OF DIFFUSION TENSOR IMAGING (DTI) IN MILD TO MODERATEL PEDIATRIC TRA

弥散张量成像 (DTI) 在轻至中度儿科手术中的敏感性

• 批准号: 7951688
• 负责人: JEFFREY ROBERT WOZNIAK
• 金额: $ 0.73万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951688
• 关键词: Adolescent; Age; Brain; Child; Clinical Research; Closed head injuries; Computer Retrieval of Information on Scientific Projects Database; Craniocerebral Trauma; Diffusion Magnetic Resonance Imaging; Funding; Grant; Institution; Magnetic Resonance Imaging; Neurocognitive; Population; Recording of previous events; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Youth; imaging modality; patient population; white matter

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to investigate the structural and neurocognitive brain differences between children/adolescents (ages 10-17) with a history of mild to moderate closed head injury and healty controls. This project seeks to demonstrate that microstructural white matter integrity may be compromised in youth who have suffered mild to moderate head injury and that these white matter abnormalities may be associated with impaired neurocognitive functioning. We propose to investigate white matter abnormalities in this population by using Diffusion Tensor Imaging (DTI), a magnetic resonance imaging (MRI) method that has not previously been used to explore this patient population.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是调查有轻度至中度闭合性脑损伤史的儿童/青少年（10-17岁）和健康对照组之间的大脑结构和神经认知差异。该项目旨在证明，微结构白色物质的完整性可能会受到损害的青年谁遭受了轻度至中度的头部损伤，这些白色物质异常可能与受损的神经认知功能。我们建议使用弥散张量成像（DTI），磁共振成像（MRI）的方法，以前还没有被用来探索这个患者群体的白色异常调查。