NON-INVASIVE MEASUREMENT OF MICROVASCULAR BLOOD FLOW DURING MILD EXTERNAL COM

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们的具体目标是： 目的：测量健康受试者和慢性静脉功能不全(CVI)患者的肌肉血流量(MBF)和皮肤血流量(SBF)，以及轻度外压引起的腿部微循环增加。 目的：测量健康受试者和慢性静脉功能不全(CVI)患者在轻度外压作用下腿部肌肉氧合的变化。 优化持续加压压力，以诱导健康受试者和CVI患者的最大微循环血流量。 目的：优化间歇气动加压(IPC)的压力、持续时间和频率，以诱导健康受试者和CVI患者的最大微循环血流量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Our specific aims are: To measure Muscle Blood Flow (MBF) and Skin Blood Flow (SBF) microcirculatory increases in the leg caused by mild external compression in healthy subjects and patients with Chronic Venous Insufficiency (CVI). To measure muscle oxygenation changes in the leg caused by mild external compression in healthy subjects and patients with Chronic Venous Insufficiency (CVI). To optimize pressures of Continuous Compression to induce maximum microcirculatory blood flow in healthy subjects and patients with CVI. To optimize compression pressures, duration, and frequency of Intermittent Pneumatic Compression (IPC) to induce maximum microcirculatory blood flow in healthy subjects and patients with CVI.