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CLINICAL TRIAL: PHASE II STUDY OF THE SAFETY & EFFICACY OF RECOMBINANT HUMAN C1

CLINICAL TRIAL: PHASE II STUDY OF THE SAFETY & EFFICACY OF RECOMBINANT HUMAN C1
临床试验：第二阶段安全性研究
批准号：
7950979
负责人：
Bruce L. Zuraw
金额：
$0.06万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-12-01 至 2009-11-30
来源：
https://reporter.nih.gov/project-details/7950979
关键词：
AcuteClinical ResearchComplement component C1sComputer Retrieval of Information on Scientific Projects DatabaseDrug KineticsFundingGrantHumanInstitutionPatientsPharmacodynamicsPhase II Clinical TrialsRecombinantsResearchResearch PersonnelResourcesSafetySourceUnited States National Institutes of Healthsafety study

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Assess the safety and tolerability of rhC1INH in symptomatic patients with HAE. Demonstrate the efficiacy of rhC1INH in the treatment of acute attacks in patients with HAE. Assess the pharmacokinetics (PK) and pharmacodynamics (PD) of rhC1INH in symptomatic patinets with HAE. Assess the safety, tolerability and effects of rhC1INH in treating subsequent attacks of HAE.
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Mechanisms Underlying the Dominant Negative Phenotype in Hereditary Angioedema
  • 批准号：
    10412915
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2019
  • 负责人：
    Bruce L. Zuraw
  • 依托单位：
    VA SAN DIEGO HEALTHCARE SYSTEM
Mechanisms Underlying the Dominant Negative Phenotype in Hereditary Angioedema
  • 批准号：
    10516092
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2019
  • 负责人：
    Bruce L. Zuraw
  • 依托单位：
    VA SAN DIEGO HEALTHCARE SYSTEM
Mechanisms Underlying the Dominant Negative Phenotype in Hereditary Angioedema
  • 批准号：
    10044412
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2019
  • 负责人：
    Bruce L. Zuraw
  • 依托单位：
    VA SAN DIEGO HEALTHCARE SYSTEM
Dual role of the bradykinin B2 receptor during inflammation
  • 批准号：
    7929357
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2010
  • 负责人：
    Bruce L. Zuraw
  • 依托单位：
    VA SAN DIEGO HEALTHCARE SYSTEM
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