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SIALIC ACID N-ACETYLNEURAMINIC ACID FROM A NATURAL FOOD SOURCE

SIALIC ACID N-ACETYLNEURAMINIC ACID FROM A NATURAL FOOD SOURCE
来自天然食物来源的唾液酸 N-乙酰神经氨酸
批准号：
7951013
负责人：
AJIT P VARKI
金额：
$0.57万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-12-01 至 2009-11-30
来源：
https://reporter.nih.gov/project-details/7951013
关键词：
AcidsClinical ResearchComputer Retrieval of Information on Scientific Projects DatabaseFoodFundingGrantHumanHuman bodyIngestionInstitutionN-Acetylneuraminic AcidN-glycolylneuraminic acidResearchResearch PersonnelResourcesSialic AcidsSourceUnited States National Institutes of Healthhuman subject

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中文摘要
翻译
该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 我们的假设是，从天然食物来源摄入人唾液酸，N-乙酰神经氨酸（Neu 5Ac），可导致从人体中消除外源唾液酸，N-羟乙酰神经氨酸（Neu 5Gc）。由于人类特有Neu 5Gc缺乏，因此本研究需要人类受试者
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Our hypothesis is that ingestion of the human sialic acid, N-acetylneuraminic acid (Neu5Ac) from a natural food source can result in the elimination of the foreign sialic acid, N-glycolylneuraminic acid (Neu5Gc), from the human body. As humans are uniquely deficient in Neu5Gc, this study requires human subjects
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