EVALUATION OF DISORDERS OF FATTY GROWTH

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 通过间接量热法评估脂肪疾病患者；通过组织学和电子显微镜评估脂肪疾病患者肌肉和脂肪异常的情况；确定脂肪疾病患者与匹配对照组之间在脂肪中的基因表达差异；确定脂肪疾病患者与匹配对照组之间的脂肪特异性FFA差异；确定脂肪疾病患者的血液和脂肪标志物；确定脂肪疾病家庭是否存在单核苷酸多态性，从而有助于深入研究这些疾病的病因学中的重要基因。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Evaluate individuals with fat disorders by indirect calorimetry; evaluate individuals with fat disorders for muscle and fat abnormalities by histology and electron microscopy; determine gene expression differences in fat between individuals with fat disorders and matched controls; determine fat-specific FFA differences between individuals with fat disorders and matched controls; determine blood and fat markers for individuals with fat disorders; determine if families with fat disorders have single nucleotide polymorphisms that may provide insight into genes important in the etiology of these disorders.