GENERAL CLINICAL RESEARCH CENTER

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 描述（由申请人提供）：自1977年以来，GCRC一直是MUSC研究企业支持和发展的关键因素。在此期间，GCRC促进了MUSC研究和研究培训活动的非凡增长。科学发现，出版跟踪记录，调查人员名单和协议在此应用程序中详细提供的生产力和GCRC在MUSC校园的重要性的证据。鉴于这一点，对全球区域中心的机构支持是非同寻常的、重要的和持续的。在这个竞争性的更新申请中，我们描述了GCRC领导团队的人员和结构的重大变化以及所提供的服务，这些服务旨在巩固和扩大GCRC在促进和催化整个校园的临床和转化研究方面的作用。培训和教育活动包括GCRC参与校园范围内的关键培训计划，如MUSC的多学科路线图T32临床博士前研究培训计划和新创建的翻译讲座系列，其中基础和临床科学家在展示合作翻译研究时共享讲台。在研究支助服务方面，全球资源中心作出了重大努力，征求用户的反馈意见，并根据这些反馈意见作出改进。我们描述了几个方面的改进，旨在提高GCRC申请流程的便利性，并提供基本协议管理方面的帮助，如监管和招聘支持。核心实验室的活动已经扩大，包括开发新的分析技术和激活100，000级洁净室（ISO 7）作为GCRC核心实验室设施。我们将继续战略努力，开发促进，催化和支持高素质的临床和转化研究和研究培训的服务。MUSC已获得P20规划拨款的资金，用于在明年制定临床和转化科学奖提案。全球区域中心将是这一举措的规划和发展不可或缺的一部分。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): The GCRC has been a critical element in the support and growth of the MUSC research enterprise since 1977. During this period, the GCRC has facilitated extraordinary growth in MUSC's research and research training activities. The scientific discoveries, publication track record, list of investigators and protocols detailed in this application provide evidence of the productivity and importance of the GCRC on the MUSC campus. In recognition of this, the institutional support for the GCRC has been extraordinary, significant and sustaining. In this competing renewal application, we describe major changes in personnel and structure of the GCRC leadership team and services offered which are designed to solidify and expand the role of the GCRC in facilitating and catalyzing clinical and translational research campus-wide. Training and educational activities include GCRC involvement in key training programs campus-wide such as MUSC's multidisciplinary Roadmap T32 clinical predoctoral research training program and a newly created translational lecture series in which basic and clinical scientists share the podium in presenting collaborative translational research. In research support services, the GCRC has made significant efforts to solicit feedback from users and make improvements based on this feedback. We describe improvements in several areas designed to increase the ease of the GCRC application process and provide assistance with basic protocol management such as regulatory and recruitment support. Core Laboratory activities have been expanded to include the development of new assay techniques and the activation of a Class 100,000 clean room (ISO 7) as a GCRC Core laboratory facility. We will continue strategic efforts to develop services that facilitate, catalyze and support high caliber clinical and translational research and research training. MUSC has received funding for a P20 planning grant to develop a Clinical and Translational Science Award proposal over the next year. The GCRC will be integral to the planning and development of this initiative.