THE EFFICACY OF LOW DOSE NALTREXONE THERAPY IN CHILDREN WITH CROHN'S

低剂量纳曲酮治疗克罗恩病儿童的疗效

• 批准号: 7951293
• 负责人: Jill P Smith
• 金额: $ 1.62万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951293
• 关键词: Child; Childhood; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Crohn' s disease; Cross-Over Studies; Dose; Double-Blind Method; Funding; Grant; Institution; Naltrexone; Patients; Placebo Control; Randomized; Research; Research Personnel; Resources; Source; United States National Institutes of Health; cohort

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The investigators hypothesize that low dose naltrexone therapy will be effective in the treatment of pediatric patients with Crohn's disease. In order to examine this hypothesis, they propose to investigate the effects of low dose naltrexone on a cohort of thirty patients with active Crohn's disease in a randomized double-blind placebo controlled cross-over trial.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 研究人员推测，低剂量纳曲酮疗法将有效治疗患有克罗恩病的儿科患者。为了检验这一假设，他们提议在一项随机双盲安慰剂对照交叉试验中，研究低剂量纳曲酮对 30 名活动性克罗恩病患者的影响。