ESTROGEN EFFECTS IN AUTOIMMUNITY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 系统性红斑狼疮（SLE）是一种典型的系统性自身免疫性疾病，不成比例地影响育龄妇女。 我们将通过白细胞去除法或静脉穿刺从狼疮患者和健康受试者中获得标本，以研究T淋巴细胞中的雌激素-雌激素受体途径。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Systemic Lupus Erythematosus (SLE) is a prototypic systemic autoimmune disease that disproportionately affects women of child-bearing age. We will obtain specimens by leukophoresis or venipuncture from lupus patients and healthy subjects to study the estrogen-estrogen receptor pathway in T lymphocytes.