ESTROGEN EFFECTS IN AUTOIMMUNITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 系统性红斑狼疮(SLE)是一种典型的系统性自身免疫性疾病，对育龄妇女的影响不成比例。我们将通过白细胞渗透或静脉穿刺法从狼疮患者和健康人身上获取标本，以研究T淋巴细胞中雌激素-雌激素受体途径。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Systemic Lupus Erythematosus (SLE) is a prototypic systemic autoimmune disease that disproportionately affects women of child-bearing age. We will obtain specimens by leukophoresis or venipuncture from lupus patients and healthy subjects to study the estrogen-estrogen receptor pathway in T lymphocytes.