THE FAMILIAL CANCER REGISTRY

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 家族癌症登记处 (FCR) 是高风险乳腺癌家族成员的信息和样本库。 FCR 对于专注于癌症危险因素、癌症易感基因识别以及癌症筛查和预防策略的研究人员来说是宝贵的资源。 FCR 收集有关个人病史、癌症家族史、癌症危险因素和癌症筛查实践的问卷数据。 每年都会联系 FCR 参与者，以获取家庭或个人病史的最新信息。 此外，FCR 还要求参与者提供血液样本，以便提取和储存 DNA 以供将来的研究使用。 FCR 还要求提供医疗记录来验证癌症诊断并验证为预防癌症而进行的手术。 最后，FCR 要求提供已进行的手术剩余的组织（肿瘤和非肿瘤）。 FCR 资源可供合格的研究人员使用，并且通常可以在不重新联系参与者的情况下提供给研究人员。 然而，当有需要时（例如癌症筛查研究），FCR 工作人员可能会就参与某些特殊研究（例如癌症筛查研究）重新联系 FCR 参与者。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Familial Cancer Registry (FCR) is a bank of information and specimens from men and women who are members of high risk breast cancer families. The FCR is a valuable resource for researchers focusing on risk factors for cancer, identification of cancer susceptibility genes, and cancer screening and prevention strategies. The FCR collects questionnaire data on personal medical history, family history of cancer, cancer risk factors, and cancer screening practices. FCR participants are contacted annually to obtain any updates to the family or personal medical histories. In addition, the FCR requests a blood sample from participants so that DNA may be extracted and stored for use in future studies. The FCR also requests medical records to verify cancer diagnoses and to verify surgeries undertaken for the prevention of cancer. Finally, the FCR requests tissue (tumor and non-tumor) leftover from surgeries already performed. FCR resources are available to qualified researchers and may often be provided to the researcher without re-contacting participants. However, FCR participants may be re-contacted by the FCR staff regarding participation in certain special studies when there is a need (e.g. cancer screening studies).