THE FAMILIAL CANCER REGISTRY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 家族性癌症登记(FCR)是一个信息库，来自乳腺癌高危家庭成员的男性和女性。对于专注于癌症风险因素、癌症易感基因识别以及癌症筛查和预防策略的研究人员来说，FCR是一个宝贵的资源。FCR收集关于个人病史、癌症家族史、癌症风险因素和癌症筛查做法的问卷数据。FCR参与者每年都会被联系，以获得任何关于家庭或个人病史的更新。此外，FCR要求参与者提供血液样本，以便提取DNA并存储用于未来的研究。FCR还要求提供医疗记录，以核实癌症诊断和为预防癌症而进行的手术。最后，FCR要求组织(肿瘤和非肿瘤)从已经进行的手术中残留下来。FCR资源可以提供给合格的研究人员，而且通常可以在不重新联系参与者的情况下提供给研究人员。然而，当有需要时，FCR的工作人员可能会就参与某些特殊研究(例如癌症筛查研究)的事宜与FCR参与者重新联系。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Familial Cancer Registry (FCR) is a bank of information and specimens from men and women who are members of high risk breast cancer families. The FCR is a valuable resource for researchers focusing on risk factors for cancer, identification of cancer susceptibility genes, and cancer screening and prevention strategies. The FCR collects questionnaire data on personal medical history, family history of cancer, cancer risk factors, and cancer screening practices. FCR participants are contacted annually to obtain any updates to the family or personal medical histories. In addition, the FCR requests a blood sample from participants so that DNA may be extracted and stored for use in future studies. The FCR also requests medical records to verify cancer diagnoses and to verify surgeries undertaken for the prevention of cancer. Finally, the FCR requests tissue (tumor and non-tumor) leftover from surgeries already performed. FCR resources are available to qualified researchers and may often be provided to the researcher without re-contacting participants. However, FCR participants may be re-contacted by the FCR staff regarding participation in certain special studies when there is a need (e.g. cancer screening studies).