THE FAMILIAL CANCER REGISTRY

家族癌症登记处

• 批准号: 7951980
• 负责人: Claudine Isaacs
• 金额: $ 16.83万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951980
• 关键词: Blood specimen; Cancer-Predisposing Gene; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; DNA; Data; Family; Family Cancer History; Funding; Future; Grant; Hereditary Malignant Neoplasm; Institution; Malignant Neoplasms; Medical History; Medical Records; Operative Surgical Procedures; Participant; Prevention strategy; Qualifying; Questionnaires; Research; Research Personnel; Resources; Risk Factors; Screening for cancer; Source; Specimen; Tumor Tissue; United States National Institutes of Health; Update; Woman; breast cancer family; cancer diagnosis; cancer prevention; cancer risk; high risk; member; men; neoplasm registry; tumor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Familial Cancer Registry (FCR) is a bank of information and specimens from men and women who are members of high risk breast cancer families. The FCR is a valuable resource for researchers focusing on risk factors for cancer, identification of cancer susceptibility genes, and cancer screening and prevention strategies. The FCR collects questionnaire data on personal medical history, family history of cancer, cancer risk factors, and cancer screening practices. FCR participants are contacted annually to obtain any updates to the family or personal medical histories. In addition, the FCR requests a blood sample from participants so that DNA may be extracted and stored for use in future studies. The FCR also requests medical records to verify cancer diagnoses and to verify surgeries undertaken for the prevention of cancer. Finally, the FCR requests tissue (tumor and non-tumor) leftover from surgeries already performed. FCR resources are available to qualified researchers and may often be provided to the researcher without re-contacting participants. However, FCR participants may be re-contacted by the FCR staff regarding participation in certain special studies when there is a need (e.g. cancer screening studies).

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 家族癌症登记局（FCR）是来自高风险乳腺癌家庭成员的信息库和标本。 对于专注于癌症危险因素，鉴定癌症易感性基因以及癌症筛查和预防策略的研究人员，FCR是一种宝贵资源。 FCR收集了有关个人病史，癌症家族史，癌症风险因素和癌症筛查实践的问卷数据。 每年与FCR参与者联系以获取家庭或个人病史的任何更新。 此外，FCR请求参与者的血液样本，以便可以提取并存储DNA以在以后的研究中使用。 FCR还要求医疗记录验证癌症诊断并验证用于预防癌症的手术。 最后，FCR请求组织（肿瘤和非肿瘤）从已经进行的手术中剩下的。 FCR资源可用于合格的研究人员，通常可以向研究人员提供而无需重新连接参与者。 但是，FCR人员可能会在需要时参与某些特殊研究（例如癌症筛查研究）。