THE FAMILIAL CANCER REGISTRY

家族癌症登记处

• 批准号: 7608313
• 负责人: Claudine Isaacs
• 金额: $ 4.93万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608313
• 关键词: Blood specimen; Cancer-Predisposing Gene; Computer Retrieval of Information on Scientific Projects Database; DNA; Data; Family; Family Cancer History; Funding; Future; Grant; Hereditary Malignant Neoplasm; Institution; Malignant Neoplasms; Medical History; Medical Records; Operative Surgical Procedures; Participant; Prevention strategy; Qualifying; Questionnaires; Research; Research Personnel; Resources; Risk; Risk Factors; Screening for cancer; Source; Specimen; Tumor Tissue; United States National Institutes of Health; Update; Woman; breast cancer family; cancer diagnosis; cancer prevention; cancer risk; member; men; neoplasm registry; tumor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Familial Cancer Registry (FCR) is a bank of information and specimens from men and women who are members of high risk breast cancer families. The FCR is a valuable resource for researchers focusing on risk factors for cancer, identification of cancer susceptibility genes, and cancer screening and prevention strategies. The FCR collects questionnaire data on personal medical history, family history of cancer, cancer risk factors, and cancer screening practices. FCR participants are contacted annually to obtain any updates to the family or personal medical histories. In addition, the FCR requests a blood sample from participants so that DNA may be extracted and stored for use in future studies. The FCR also requests medical records to verify cancer diagnoses and to verify surgeries undertaken for the prevention of cancer. Finally, the FCR requests tissue (tumor and non-tumor) leftover from surgeries already performed. FCR resources are available to qualified researchers and may often be provided to the researcher without re-contacting participants. However, FCR participants may be re-contacted by the FCR staff regarding participation in certain special studies when there is a need (e.g. cancer screening studies).

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 家族性癌症登记处（FCR）是一个信息库和样本，来自高危乳腺癌家族的男性和女性成员。 FCR是研究人员关注癌症风险因素，癌症易感基因鉴定以及癌症筛查和预防策略的宝贵资源。 FCR收集关于个人病史、癌症家族史、癌症风险因素和癌症筛查实践的问卷数据。 每年联系FCR参与者，以获得家族或个人病史的任何更新。 此外，FCR要求从参与者那里提取血液样本，以便提取和储存DNA，供未来研究使用。 联邦癌症委员会还要求提供医疗记录，以核实癌症诊断，并核实为预防癌症而进行的手术。 最后，FCR要求从已经执行的手术中剩余的组织（肿瘤和非肿瘤）。 FCR资源可供合格的研究人员使用，并且通常可以提供给研究人员而无需重新联系参与者。 但是，FCR工作人员可能会在需要时就参与某些特殊研究（例如癌症筛查研究）再次联系FCR受试者。