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THE MOLECULAR BASIS FOR COGNITIVE IMPAIRMENT IN PARKINSON'S DISEASE: A PET STUDY

THE MOLECULAR BASIS FOR COGNITIVE IMPAIRMENT IN PARKINSON'S DISEASE: A PET STUDY
帕金森病认知障碍的分子基础:宠物研究
批准号:
7951927
负责人:
ANDREW FEIGIN
金额:
$0.03万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-04-01 至 2010-03-31

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cognitive deficits occur in Parkinson's disease (PD) and the cause is currently unknown. We propose a novel study utilizing multi-tracer positron emission tomography (PET) imaging to investigate the pathophysiology of cognitive impairment in non-demented PD patients. We hypothesize that aggregated protein deposits associated with Lewy body in the cortical regions may correlate with abnormal metabolic activity and underlie cognitive dysfunction.
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会议论文
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Brain Network Imaging: A Novel Biomarker for Preclinical Huntington's Disease
Brain Network Imaging: A Novel Biomarker for Preclinical Huntington's Disease
CLINICAL TRIAL: A STUDY OF CREATINE IN SUBJECTS WITH TREATED PARKINSON'S DISEASE
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